Atrial Fibrillation Prevention in Post Coronary Artery Bypass Graft Surgery With Cryoablation for Ganglionic Plexi

Not Applicable

Withdrawn

• Conditions: Complication of Coronary Artery Bypass Graft; Atrial Fibrillation
• Interventions: Procedure: Two sites cryoablation

• Registration Number: NCT02035163
• Lead Sponsor: Yong Seog Oh

Brief Summary

Atrial fibrillation after coronary artery bypass graft is a common complication.

The investigators have thought that the mechanism of temporarily postoperative atrial fibrillation is closely related to the autonomic nervous system imbalance.

In a last several years, cryoablation was substituted for atrial incision in many reports to simplify the maze procedure.

However, there has been no comparative study to delineate the feasibility of the use of cryoablation.

Detailed Description

Modified maze procedures that use energy sources for the ablation of atrial fibrillation concomitant with cardiac surgery have been shown to improve outcomes in patients with atrial fibrillation. Cryoablation of atrial fibrillation recently has been shown to lead to outcomes that were at least equivalent to those reported for other energy modalities over both short- and medium-term follow-up times.

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2014-01-10
• Study First Submitted QC: 2014-01-10
• Study First Posted: 2014-01-14
• Primary Completion: 2019-12
• Study Completion: 2019-12
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-20
• Last Update Posted: 2024-04-23

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• coronary artery graft bypass patient
• sinus rhythm

Exclusion Criteria

• Patients using antiarrhythmic
• severe hypotension after surgery ( systolic blood pressure <90mmHg)
• history of atrial fibrillation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Two sites cryoablation group	Two sites cryoablation	Two ganglionic plexi around atrium was performed with 90-second cryoablation.

Primary Outcome Measures

Name	Time	Method
freedom of atrial fibrillation or other atrial arrhythmia	5 days after surgery	check the occurrence of atrial fibrillation through EKG monitoring And bradycardia(\<40/min) or tachycardia(\>110/min) does not occur

Trial Locations

Locations (1)

The Catholic University of Korea, Seoul St Mary's Hospital; 🇰🇷 Seoul, Seo Cho Gu, Korea, Republic of