A comparison of the development of collateral blood vessels in participants with branch retinal vein occlusion and hemicentral retinal vein occlusion.

Not Applicable

Withdrawn

• Conditions: Hemi-central retinal vein occlusion; Branch retinal vein occlusion; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12617001281381
• Lead Sponsor: ions Eye Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-09-06
• Last Update Posted: 28 June 2021

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

1. Dry macula for three months following anti-VEGF treatment.
2. Access to participants medical notes including Fluorescein angiograms (FA).

Exclusion Criteria

1. Inability to fixate for OCT-A image acquisition.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine whether hemi-CRVOs develop more haemodynamically efficient collateral circulation compared to BRVOs. [Comparison of OCT-A images between the hemi-CRVO and BRVO groups taken at the study visit. ];To determine whether hemi-CRVO participants require less anti-VEGF treatment compared to BRVO participants.[The medical records of the participants will be reviewed to determine the number of anti-VEGF treatments each participant has received during their treatment phase prior to entry into the study. ];To compare the time it takes for the hemi-CRVOs to resolve compared to the BRVOs.[The medical records of the participants will be reviewed. The FA images taken during the participant's treatment (prior to entry into the study) will be used to determine how long it has taken for the occlusion to resolve in both study groups.]

Secondary Outcome Measures

Name	Time	Method
To quantify the size of collaterals in participants with Hemi-CRVO and BRVO by using OCT-A and FA images. [Analysis of OCT-A and FA images taken at the study visit. ];To quantify the number of collaterals in participants with hemi-CRVO and BRVO by using OCT-A and FA images. [Analysis of the OCT-A and FA images taken at the study visit. ]