Efficacy of Narrow Band Imaging (NBI) and Computed Tomography (CT) following head and neck cancer treatment.

Not Applicable

• Conditions: Lung cancer; Head and Neck Cancer; Surveillance for second primary cancer; Cancer - Head and neck; Cancer - Lung - Non small cell

• Registration Number: ACTRN12616000581460
• Lead Sponsor: Royal Brisbane and Womens Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Patients 3-5 years post completion of curative treatment of Head and Neck Cancer ( either surgery or chemoradiation.)

Exclusion Criteria

Severe COPD or active coronary artery disease making bronchoscopy unsafe

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Yield of preneoplastic lesions in the upper airway and bronchus as detected by white light bronchoscopy and NBI bronchoscopy. The outcome is measured by HISTOLOGY YIELD BY WHITE LIGHT VERSUS NBI- The important pathology is moderate dysplasia or worse up to carcinoma in situ.<br><br>[At bronchoscopy/upper airway inspection];Yield of malignant lesions by CT chest[At time of bronchoscopy]

Secondary Outcome Measures

Name	Time	Method
Correlation between yield of abnormal lesions using NBI and COPD severity. COPD assessed using the GOLD classification of lung function severity.<br>Yield of lesions of moderate dysplasia or worse will be expressed comparing Gold class 0-2 with Gold Class 3-4.[At time of bronchoscopy]