Assessment of Diagnostic Performance and Role of Ga-68 PSMA-11 PET/CT in Patients with Advanced Hepatocellular Carcinoma
- Conditions
- Neoplasms
- Registration Number
- KCT0008628
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Patients who are older than19 years and capable of providing signatures in consent forms
- Patients diagnosed with or suspected primary hepatocellular carcinoma by clinical information (blood test AFP, PIVKA elevation, etc.), imaging or pathology.
- Patients with BCLC stage B or higher grade
- Patients who have performed or are scheduled to perform tri-phase abdominal pelvic CT within a four-week period before Ga-68 PSMA-11 PET/CT and a two-week period after Ga-68 PSMA PET/CT after study enrollment
- Patients who are willing to make a follow-up observation in our hospital for at least 6 months after study enrollment
- If other primary cancers other than liver cancer were previously diagnosed or occurred at the same time
- Patients within 3 weeks after chemotherapy or within 4 weeks after hepatic artery chemoembolization
- Patients are under severe and/or uncontrolled and/or unstable medical conditions (e.g., congestive heart failure, acute myocardial infarction, degenerative brain disease, severe lung disease, etc.)
- Patients who cannot stably perform CT or PET/CT imaging tests due to claustrophobia, dyskinesia, anxiety disorders, and etc
- Where it is determined that the patient will not be eligible to completely collect data for clinical trials due to personal circumstances or other reasons
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection sensitivity and positive predictive value of Ga-68 PSMA-11 PET/CT
- Secondary Outcome Measures
Name Time Method Additional diagnostic value of Ga-68 PSMA-11 PET/CT to conventional CT ;Comparison of staging (BCLC) before and after adding Ga-68 PSMA-11 PET/CT