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STUDY COMPARING ONDANSETRON AND PALONOSETRON IN REDUCING VOMITING IN PATIENTS AFTER ENT SURGERIES

Not Applicable
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2024/03/063674
Lead Sponsor
DR SOMSUNDAR R G
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Aged between 18 to 60 years

2.ASA I and II category patients

3.Patients undergoing elective otorhinolaryngology surgeries under general anaesthesia

4.Patients willing to give informed consent to participate in the study.

Exclusion Criteria

1.Allergy to palonosetron and ondensetron

2.Use of antiemetics within 48 hours prior to surgery

3.Patient refusal

4.Patient with prolonged QT syndrome

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare the efficacy of ondansetron versus palonosetron in preventing postoperative nausea and vomiting in the first 24 hours using three scoring systems (nausea score, postoperative vomiting score, and postoperative nausea and vomiting score) in patients undergoing elective otorhinolaryngology surgeries under general anaesthesiaTimepoint: at base line , 2 hours , 6 hours , 12 hours , 24 hours
Secondary Outcome Measures
NameTimeMethod
To measure the severity of nausea, need for rescue medication, patient’s satisfaction and incidence of adverse effects. <br/ ><br> <br/ ><br>Timepoint: 0 to 2 hrs, 2 to 6 hrs, 6 to 24 hrs
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