Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Osteoarthritis of the Knee
- Sponsor
- Ben-Gurion University of the Negev
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Pain control
- Status
- Terminated
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of this study is to determine whether an intraarticular injection of Ozone into the knee joint is an effective therapy for pain control in patients with osteoarthritis of the knee.
Detailed Description
Ozone, as a gas made of three atoms of oxygen with a cyclic structure, has been used as a medical therapy from the mid ninetieth century. Today, this therapy is a recognized modality in many European and Latin American nations for orthopedic problems, infections, ischemic diseases, and skin problems. However, despite of this wide use internationally, there is minimal mention of this treatment modality in the Anglo-American literature. The present is the first of a series of studies planned to scientifically test the effectiveness of ozone as a main-stream therapy, introducing it to the Anglo-American literature. In this first study we will check whether intraarticular injections of Ozone into the knee joint are effective as a therapy for pain control in patients with osteoarthritis of the knee.
Investigators
Howard Tandeter
POB 653 Beer Sheva
Ben-Gurion University of the Negev
Eligibility Criteria
Inclusion Criteria
- •Osteoarthritis of knee
Exclusion Criteria
- •Positive rheumatologic serologic tests
- •Cognitive impairment
- •Adjacent osteomyelitis
- •Bacteremia
- •Hemarthrosis
- •Impending (scheduled within days) joint replacement surgery
- •Infectious arthritis
- •Joint prosthesis
- •Osteochondral fracture
- •Periarticular cellulitis
Outcomes
Primary Outcomes
Pain control
Time Frame: 6 months