Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients

Completed

• Conditions: Bipolar Disorder

• Registration Number: NCT01992302
• Lead Sponsor: Hospital Clinic of Barcelona

Brief Summary

In this study we tried to elucidate the factors associated with the development of a rapid cycling course in bipolar disorder patients, in a prospective and longitudinal design, and the role of antidepressants. The identification of risk factors is extremely relevant from the clinical point of view. We hypothesized that rapid cycling bipolar disorder is associated with more chronicity, poor outcome, and more antidepressant prescription.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-06
• Status Verified: 2013-11
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Study First Submitted: 2013-11-06
• Study First Submitted QC: 2013-11-18
• Last Update Submitted: 2013-11-18
• Study First Posted: 2013-11-25
• Last Update Posted: 2013-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 289

Inclusion Criteria

• Bipolar I and II disorder patients according to DSM-IV criteria

Exclusion Criteria

• Major medical comorbidities, voluntary drop-out from study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of patients who develop rapid cycling	8 years

Secondary Outcome Measures

Name	Time	Method
Factors associated with the development of a rapid cycling course in bipolar disorder patients	8 years

Trial Locations

Locations (1)

Barcelona Bipolar Disorders Program, Hospital Clinic Barcelona; 🇪🇸 Barcelona, Catalonia, Spain