A Phytochemical In Silico and Clinical Study of Mustadi Gana Kwatha and Swadamstradi Taila in the management of Benign Prostatic Hyperplasia
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Disease specific subjective parameters based on IPSS score
研究概览
简要总结
On the basis of previous data and disease prevalence a total sample size of 25 has calculated after statistical analysis.Patients with signs and symptoms of BPH will be selected from OPD/IPD of department of Shalya Tantra and included in a single interventional group. Complete evaluation will be done by clinical examination, hematological, biochemical, radiological, urine analysis and uroflowmetry studies. Patients will be treated with Kala Basti for a period of 15 days;10 anuvasana basti with Swadamstradi Taila and 5 kashaya basti with Mustadi Gana Kashaya. After completion of therapy it will be assessed by subjective and objective parameters including urine flowrate(UFR), Post Voidal Residual Urine(PVRU) and size of prostate by USG. Statistical analysis, Phytochemical ,In Silico study will be conducted on a computer through computational simulations. The biochemical, biophysical, biosaftey ,toxicity study and theraputics of Mustadi Gana Kashaya and Swadamstardi Taila will be studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 40.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- Male
入选标准
- •diagnosed cases of BPH, without acute retention of urine all grades of BPH without acute retention of urine.
排除标准
- •Patients with bladder neck stenosis acute urinary retention known case of systemic diseases like TB Hepatitis B HIV Hepatitis C Cardiac diseases uncontrolled DM urethral stricture Neurogenic bladder ARF and CRF veneral diseases.
结局指标
主要结局
Disease specific subjective parameters based on IPSS score
时间窗: Basti will be administered for a period of 15 days followed by follow up every 4 weeks for a period of 12 weeks
objective parameters like weight of prostate and PVRU by USG whole abdomen with prostate and PVRU
时间窗: Basti will be administered for a period of 15 days followed by follow up every 4 weeks for a period of 12 weeks
次要结局
- Relief in signs and symptoms of BPH(for a period of 3months)
研究者
Dr Saradhi R
Banaras Hindu University