A pilot study to compare pharmacognostical, phytochemical, and therapeutic effect of Brihat Agnimantha (Premna integrifolia) and Laghu Agnimantha (Clerodendrum phlomidis) mool kwath in the management of Sthaulya (obesity).
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Reduction in the sign and symptoms of Sthaulya(Obesity).
研究概览
简要总结
The study presented focuses on the pharmacognostical, sephytochemical, and therapeutic aspects of two species of Agnimanth Brihat Agnimanth Premna integrifolia and Laghu Agnimanth Clerodendrum phlomidis in the context of treating Sthaulya obesity in Ayurveda
Pharmacognostical Study This involves the identification and standardization of Agnimanth species, crucial for authentication and prevention of adulteration. Initial research highlighted variations in pharmacognostical characteristics and phytochemical profiles between the two species.
Phytochemical Study Evaluating the constituents of Agnimanth species and their decoctions Kwath is essential to understand their bioactive components and therapeutic potential. Such studies aim to establish similarities or differences in formulations derived from these species.
Therapeutic Study Ayurvedic texts like Charak Samhita advocate Agnimanth as a treatment for Sthaulya, emphasizing its role in balancing doshas and improving Jatharagni to manage pathological increases in appetite. Modern research underscores the need to identify the most effective Agnimanth species for obesity management.
The need for pharmacognostical and phytochemical studies precedes therapeutic investigations, ensuring the identification and standardization of plant materials. This foundational work is essential for validating Ayurvedic treatments and developing effective herbal formulations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient having Clinical sign & symptom of Sthaulya as per Ayurvedic text. 2.Patient either sex between the Age group of
- •60year . 3.Patient having BMI more than or equal to 25kg/m2.
排除标准
- •1.Patient below the age of 18 years and above 60 years 2.Patient of any chronic diseases 3.Pregnant and lactating women 4.Discontinuation criteria Any Acute or Severe Illness.
- •Patient not willing to continue the treatment.
结局指标
主要结局
Reduction in the sign and symptoms of Sthaulya(Obesity).
时间窗: After treatment of 60 days
次要结局
- Changes in the subjective parameters.(after treatment period of 60 days.)
研究者
Dr Rakesh Kumar
Institue for Ayurved studies and Research