Effects of Transcranial Direct Current Stimulation (tDCS) on Motor Function in Schizophrenia Patients and Individuals at Risk for Psychotic Onset

Not Applicable

Recruiting

• Conditions: Schizophrenia; Psychosis; Parkinsonism; Dyskinesias

• Registration Number: NCT04086160
• Lead Sponsor: Dr WANG Shumei

Brief Summary

The purposes of this research are to investigate (1) if schizophrenia patients and at-risk individuals present bradykinesia and dyskinesia and (2) if tDCS improves motor performance in schizophrenia patients and at-risk individuals. The first hypothesis is that both schizophrenia patients and at-risk individuals show bradykinesia and dyskinesia, and the motor symptoms are more severe in the former than the latter. The second hypothesis is that tDCS improves motor performance in schizophrenia patients and at-risk cases.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-07-27
• Study Start: 2019-08-22
• Study First Submitted QC: 2019-09-09
• Study First Posted: 2019-09-11
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-27
• Last Update Posted: 2023-03-01
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Motion analysis by using an eight-camera motion capture system (VICON; Oxford Metrics Group, Oxford, UK)	Within one week right after the 8th (last) session of tDCS	normalized number of movement units (representing severity of dyskinesia). Unit: units/mm

Trial Locations

Locations (1)

Hong Kong Polytechnic University; 🇭🇰 Kowloon, Hong Kong