The effect of medication for social anxiety disorder upon the production of chemical messengers in the brai

Not Applicable

• Conditions: Social anxiety disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN66537707
• Lead Sponsor: ppsala university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-08
• Last Update Posted: 15 May 2023
• Study Completion: 2023-05-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1. Social anxiety disorder according to DSM-5, must be the main diagnosis as assessed with the structured clinical interview for DSM disorders (SCID) and the MINI interview
2. Otherwise somatically healthy
3. Age 18-64
4. Willingness to participate in a brain imaging trial (giving informed consent)

Exclusion Criteria

1. Treatment of social anxiety within the three months preceding the study
2. Current serious or dominant psychiatric disorder other than social anxiety disorder (e.g. psychosis, major depressoin, bipolar disorder)
3. Suicidal ideation
4. Chronic use of other prescribed medication that could influence the results (e.g. antidepressants, anxiolytics, certain sleeping pills and herbal drugs like St John's Wort)
5. Abuse of alcohol or narcotics
6. Pregnancy of planned pregnancy during the study period
7. Menopause
8. Previous PET examination
9. Contraindications for MRI investigation (e.g implants or other metal objects in the body, brain and heart operations)
10. Heart insufficiency or previous heart surgery
11. Contraindications for treatment with escitalopram

Study & Design

• Study Type: Interventional
• Study Design: Not specified