Effects of dietary administration of n-3 polyunsaturated fatty acids on cardiac electrophysiology in humans

Not Applicable

Recruiting

• Conditions: supraventricular tachycardia; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12608000341325
• Lead Sponsor: Royal Adelaide Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-07-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

undergoing an elective cardiac electrophysiology procedure (electrophysiology study +/- ablation for supraventricular tachycardia

Exclusion Criteria

a) Cardiac rhythm other than sinus rhythm at the time of the procedure
b) Current use of fish oil supplements
c) Known impaired lipid metabolism
d) Uncontrolled diabetes mellitus
e) Known allergy to fish
f) Current use of anti-arrhythmics other than ß-blockers, or use of amiodarone within the past 3 months
g) New York Heart Association Grade II-IV heart failure
h) Known bleeding disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Atrial refractory periods at a) high lateral right atrium b) low lateral right atrium c) proximal coronary sinus d) distal coronary sinus e) High atrial septum[at time of electrophysiology study/ablation ie at day 21];Conduction velocity: a) Total conduction time (lateral right atrium to distal coronary sinus), b) Coronary sinus, c) Lateral right atrium[at time of electrophysiology study/ablation ie at day 21];corrected sinus node recovery time[at time of electrophysiology study/ablation ie at day 21]

Secondary Outcome Measures

Name	Time	Method
Wenckebach cycle length of the atrio-ventricular node[at time of electrophysiology study/ablation ie at day 21]