Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment

Not Applicable

Completed

• Conditions: Dentin Sensitivity; Dentine Hypersensitivity; Hypersensitivity Dentin; Dentin Hypersensitivity
• Interventions: Drug: Resin modified glass ionomer; Drug: Potassium Nitrate 2%; Procedure: Low level laser therapy

• Registration Number: NCT02931734
• Lead Sponsor: Federal University of Uberlandia

Brief Summary

The aim of this study is through a randomized clinical trial, double blind, splith-mouth, evaluate the various types of protocols and clinical efficacy in the reduction or even elimination of dentinal hypersensitivity by the agents Desensibilize KF - FGM Dental Products, Clinpro - 3M Company, Minnesota - USA, Photon Laser III - DMC, Brazil, Desensibilize KF and laser, Desensibilize KF and Clinpro, laser and Clinpro and the association of all products. Data will be collected, tabulated and submitted to statistical analysis.

Detailed Description

Cervical dentin hypersensitivity is a painful condition and is a clinical challenge due to different treatment strategies available. The aim of this study is through a randomized clinical trial, double blind, splith-mouth, evaluate the various types of protocols and clinical efficacy in the reduction or even elimination of dentinal hypersensitivity. A hundred forty teeth of healthy patients of both sexes were selected. Visual Analog Scale was used pain (VAS) to measure the intensity of the patient's pain. The teeth will be randomly divided into 7 different groups according to the desensitization treatment under study: Desensibilize KF - FGM Dental Products, Clinpro - 3M Company, Minnesota - USA, Photon Laser III - DMC, Brazil, Desensibilize KF and laser, Desensibilize KF and Clinpro, laser and Clinpro and the association of all products. Data will be collected, tabulated and submitted to statistical analysis.

Study Timeline

• Study Start: 2014-10
• Primary Completion: 2015-01
• Study Completion: 2015-07
• Status Verified: 2016-10
• Study First Submitted: 2016-10-03
• Study First Submitted QC: 2016-10-12
• Study First Posted: 2016-10-13
• Last Update Submitted: 2016-10-13
• Last Update Posted: 2016-10-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• presence of dentin exposure lesions with clinical diagnosis of moderate or severe tooth sensitivity
• good oral hygiene.

Exclusion Criteria

• cavities,
• presence of periodontal disease and or parafunctional habits,
• cracks or enamel fractures,
• extensive or unsatisfactory restorations,
• recent restorations involving the labial surface,
• dentures,
• orthodontics.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
RMGI, KF, LLLT	Low level laser therapy	Resin modified glass ionomer, potassium nitrate and sodium fluoride 2% and Low level laser therapy - GaAlAs ; an application of the three associated products, every 48 hours; 4 sessions.
Resin modified glass ionomer (RMGI)	Resin modified glass ionomer	Resin modified glass ionomer; an application every 48 hours; 4 sessions.
Low level laser therapy - GaAlAs (LLLT)	Low level laser therapy	Low level laser therapy - GaAlAs; an application every 48 hours; 4 sessions.
RMGI and KF	Resin modified glass ionomer	Resin modified glass ionomer and potassium nitrate and sodium fluoride 2%; an application of the two associated products, every 48 hours; 4 sessions.
RMGI and LLLT	Resin modified glass ionomer	Resin modified glass ionomer and Low level laser therapy - GaAlAs; an application of the two associated products, every 48 hours; 4 sessions.
RMGI and LLLT	Low level laser therapy	Resin modified glass ionomer and Low level laser therapy - GaAlAs; an application of the two associated products, every 48 hours; 4 sessions.
KF and LLLT	Low level laser therapy	Potassium Nitrate and Sodium fluoride 2% and Low level laser therapy - GaAlAs; an application of the two associated products, every 48 hours; 4 sessions.
Potassium Nitrate 2% (KF)	Potassium Nitrate 2%	Potassium Nitrate and Sodium fluoride 2%; an application every 48 hours; 4 sessions.
RMGI and KF	Potassium Nitrate 2%	Resin modified glass ionomer and potassium nitrate and sodium fluoride 2%; an application of the two associated products, every 48 hours; 4 sessions.
KF and LLLT	Potassium Nitrate 2%	Potassium Nitrate and Sodium fluoride 2% and Low level laser therapy - GaAlAs; an application of the two associated products, every 48 hours; 4 sessions.
RMGI, KF, LLLT	Potassium Nitrate 2%	Resin modified glass ionomer, potassium nitrate and sodium fluoride 2% and Low level laser therapy - GaAlAs ; an application of the three associated products, every 48 hours; 4 sessions.
RMGI, KF, LLLT	Resin modified glass ionomer	Resin modified glass ionomer, potassium nitrate and sodium fluoride 2% and Low level laser therapy - GaAlAs ; an application of the three associated products, every 48 hours; 4 sessions.

Primary Outcome Measures

Name	Time	Method
Level of cervical dentin hypersensitivity, measured by visual analog scale	24 weeks	Evaluate the reduction in Cervical Dentin Hypersensitivity with a 24 weeks follow up.

Trial Locations

Locations (1)

Federal University of Uberlandia; 🇧🇷 Uberlandia, Minas Gerais, Brazil