Outcome of ICSI Using Cryopreserved Testicular Sperm From Infertile Men With Varicocele-associated Azoospermia
试验速览
- 阶段
- 不适用
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Clinical pregnancy: documentation of gestational sac and fetal pulsation by transvaginal US 15 days after B-HCG assessment.
研究概览
简要总结
This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in an ART program in Sohag. Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files.
详细描述
Study approval: The study will be submitted for approval by Research and Ethical committees at Faculty of Medicine, Sohag University.
This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in an ART program in Sohag .
Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files.
Study design: Prospective, controlled clinical study. Control group: ICSI cases using cryopreserved sperms from infertile azoospermic men due to etiologies other than varicocele. Cases with known female factor infertility will be excluded.
Outcome Measures: fertilization rate, embryo quality, chemical pregnancy and clinical pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in aى ART program.
- •ICSI cases using cryopreserved sperms from infertile azoospermic men due to etiologies other than varicocele.
排除标准
- •Cases with known female factor infertility
结局指标
主要结局
Clinical pregnancy: documentation of gestational sac and fetal pulsation by transvaginal US 15 days after B-HCG assessment.
时间窗: 6/2014 up to one year.
次要结局
- Chemical pregnancy: B-human chorionic gonadotropin (B-HCG) at day 15 after embryo transfer.(6/2014 up to one year.)
- Fertilization Rate: percentage of fertilized oocyte.(6/2014 up to one year.)
- Embryo Quality: morphological assessment of the developing embryo.(6/2014 up to one year.)
研究者
Mohamed Al-Hussini Jad Abdel-latif, M.B.B.Ch.
Egypt - Sohag - Nasser City - Sohag University - Faculty Of Medicine - Dermatology, Venereology and Andrology Department
Sohag University