NL-OMON53957
Recruiting
Not Applicable
Antibiotics vs antibiotics and Surgical ThERapy for Infective endocarditis - ASTERIx
niversity Hospital of Copenhagen, Rigshospitalet0 sites30 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- endocarditis
- Sponsor
- niversity Hospital of Copenhagen, Rigshospitalet
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Definite left\-sided infective endocarditis
- •Valve vegetation \=\>10 mm AND \<\=30 mm with 1 or no previous embolic event
- •during current infective endocarditis case
Exclusion Criteria
- •Unwilling to sign informed consent
- •At least one clear class I recommendation for surgery because of heart
- •failure or uncontrolled local infection (abscess, false aneurysm, fistula)
- •Unavailable for follow\-up (e.g. tourist)
- •At least one of the following criteria (unsuitable for surgery):
- •Intracranial hemorrhage \<1 month
- •Life expectancy \<1 year
- •Age \>\=85 years
- •BMI below 15 or above 45
- •Possible severe liver cirrhosis (Child\-Pugh Class B or worse)
Outcomes
Primary Outcomes
Not specified
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