Efficacy of Combined Intense Pulsed Light (IPL) With Fractional Erbium:YAG Laser Ablation in Scar Prevention
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Patient Observer Scar Assessment Scale
研究概览
简要总结
The scar site was divided into 3 sites; combined IPL/fractional Er:YAG laser treatment site, fractional Er:YAG laser treatment site and untreated control site. At baseline, three lesions were randomized to IPL / fractional Er:YAG laser combination therapy site, fractional Er:YAG laser treatment alone site, and untreated control site. The laser treatment was conducted total three sessions, immediately at suture removal (baseline), 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment (20 weeks after suture removal).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of postoperative scars on the abdomen
- •scars were symmetrical shaped in a line of 3cm or more
排除标准
- •uncontrolled systemic or chronic disease
- •hypersensitive to the ingredients
- •a history of other laser treatments within the past 6 months
- •pregnancy
- •lactation
- •Recent sun exposure
结局指标
主要结局
Patient Observer Scar Assessment Scale
时间窗: 20 weeks
The POSAS observer consists of following 6 items: vascularity, pigmentation, thickness, surface area, relief, pliability. Each item was evaluated on a scale from 1 (normal skin) to 10 (worst scar). Finally, the POSAS total score was calculated as the sum of six items, ranging from 6 to 60.
次要结局
- Total Vancouver Scar scale(20 weeks)
- Erythema index(20 weeks)
- Melanin index(20 weeks)
研究者
Bo Young Chung
Principal Investigator, Clinical Professor
Hallym University Kangnam Sacred Heart Hospital