Postoperative CRP Levels and Vaginal Cuff Hematoma

Completed

• Conditions: Postoperative Hematoma

• Registration Number: NCT03879499
• Lead Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Brief Summary

After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications.

A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2018-01-01
• Study Completion: 2018-01-01
• Study First Submitted: 2019-03-12
• Study First Submitted QC: 2019-03-15
• Study First Posted: 2019-03-18
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-17
• Last Update Posted: 2024-07-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 106

Inclusion Criteria

women who underwent TLH operation with benign gynecological indications

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Exclusion Criteria

• Decided to switch to laparotomy during operation
• postoperative complication due to relaparotomy
• infection (including urinary system and lung infections)
• Blood transfusion after TLH
• with rheumatic diseases
• length of hospital stay due to wound infection

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement	15 days	The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.
Relationship between CRP Levels and cuff hematoma; crp levels	1 week	The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.