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临床试验/NCT03052621
NCT03052621已完成不适用

Revisiting Omental Transposition in Locally Advance and Locally Recurrent Breast Cancer

Queen Sirikit Centre for Breast Cancer1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 1994年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1
主要终点
Survival time

研究概览

简要总结

Locally advance breast cancer and extensive locoregional recurrence are still considered as complexity of reconstruction. Although previous studies concluded that omental transposition was considerably indicated in poor vascularity in irradiated tissue, secondary infection and large defect become the obstacles of local tissue flaps. While some centres showed the excellent healing of omental transposition. Meanwhile, many studies showed the preferable outcome in escalating radiotherapy in term of locoregional control. In the investigators' institute, omental transposition in breast cancer has been developed for twenty years. The only institute in Thailand enhanced using this procedure in order to closure of large primary breast cancer and chest wall recurrence. This procedure is undertaken by single surgeon (Dr. K.J.). The investigators' protocol of omental transposition is including preoperative chemotherapy, preoperative accelerated radiation up to 80 Gy, approval of breast cancer centre committee, and meticulous wound care including vacuum assisted wound dressing, non-adhesive dressing. As a result, survival time could be improved.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • The patients with omental transposition operation within King Chulalongkorn Memorial Hospital
  • More than 18 years of age

排除标准

  • The patients with refusal

结局指标

主要结局

Survival time

时间窗: 22 years

次要结局

未报告次要终点

研究者

发起方
Queen Sirikit Centre for Breast Cancer
申办方类型
Other
责任方
Principal Investigator
主要研究者

Sikrit Denariyakoon

Doctor

Queen Sirikit Centre for Breast Cancer

研究点 (1)

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