Revisiting Omental Transposition in Locally Advance and Locally Recurrent Breast Cancer
- Conditions
- Survival Rate
- Registration Number
- NCT03052621
- Lead Sponsor
- Queen Sirikit Centre for Breast Cancer
- Brief Summary
Locally advance breast cancer and extensive locoregional recurrence are still considered as complexity of reconstruction. Although previous studies concluded that omental transposition was considerably indicated in poor vascularity in irradiated tissue, secondary infection and large defect become the obstacles of local tissue flaps. While some centres showed the excellent healing of omental transposition. Meanwhile, many studies showed the preferable outcome in escalating radiotherapy in term of locoregional control. In the investigators' institute, omental transposition in breast cancer has been developed for twenty years. The only institute in Thailand enhanced using this procedure in order to closure of large primary breast cancer and chest wall recurrence. This procedure is undertaken by single surgeon (Dr. K.J.). The investigators' protocol of omental transposition is including preoperative chemotherapy, preoperative accelerated radiation up to 80 Gy, approval of breast cancer centre committee, and meticulous wound care including vacuum assisted wound dressing, non-adhesive dressing. As a result, survival time could be improved.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 40
- The patients with omental transposition operation within King Chulalongkorn Memorial Hospital
- More than 18 years of age
- The patients with refusal
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival time 22 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Queen Sirikit Centre for Breast Cancer
🇹🇭Bangkok, Thailand
Queen Sirikit Centre for Breast Cancer🇹🇭Bangkok, Thailand