Comparison of different retransfusion strategies in cardiothoracic surgery

Completed

• Conditions: Coronary artery bypass graft surgery; 10007593

• Registration Number: NL-OMON32819
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 56

Inclusion Criteria

Patients undergoing coronary artery bypass surgery (CABG)
Use of cardiopulmonary bypass (CPB)
Age 18-75 years
Informed consent

Exclusion Criteria

Re-operations
Patient with hereditary hematological/coagulation disorders
Emergency operation
Body surface area (BSA) 1.7 < BSA > 2.3
Patient with anemia (Hb < 6.0)
Patients receiving blood transfusions < 3 months before operation
Patients receiving blood transfusion before or during extracorporeal circulation
Insulin depended diabetes mellitus
Patients who are currently participating in another clinical trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Number of homologous bloodtransfusions after cardiopulmonary bypass. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Demographic variables: Age, gender, length, body weight, preoperative and<br /><br>postoperative hematocrit, hemoglobin, leukocyte count, IL-6 & DPG.<br /><br>Surgical characteristics: Surgery time, clamp time, CPB time, blood loss,<br /><br>arterial gasses pre-, intra- and postoperatively.</p><br>