Efficacy of Buccal Pad of Fat, Advanced Platelet Rich Fibrin, Fibrin Glue and Oxidized Cellulose Plug in Management of Oro-Antral Communication, Comparative Clinical Study

Not Applicable

Completed

• Conditions: Healthy Volunteers Only
• Interventions: Procedure: oxidized cellulose; Procedure: Buccal Pad of Fat; Procedure: A-PRF; Procedure: fibrin glue

• Registration Number: NCT06220877
• Lead Sponsor: October 6 University

Brief Summary

Evaluation of the efficacy of different treatment protocols in the management of Oro-Antral Communications.

Detailed Description

the current study was carried on 24 patients suffering from Oro-Antral Communications. All patients were divided into 4 equal groups.

Study Timeline

• Study Start: 2019-01-01
• Primary Completion: 2023-01-01
• Study Completion: 2023-06-01
• Status Verified: 2024-01
• Study First Submitted: 2024-01-13
• Study First Submitted QC: 2024-01-13
• Last Update Submitted: 2024-01-13
• Study First Posted: 2024-01-24
• Last Update Posted: 2024-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• patients suffering from oroantral communications
• patients suffering from oroantral fistula.
• The Diameter of the opening ranged from 4-9 mm,
• communication resulted from recent extraction,
• foreign body; or
• cyst enucleation

Exclusion Criteria

Patients suffering from any systemic diseases were excluded from the study.

• diabetes,
• autoimmune diseases,
• cancers,
• nephropathy,
• coagulation disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group IV	oxidized cellulose	oxidized regenerated cellulose plug have been used for management of OAC.
Group I	Buccal Pad of Fat	patients were treated using Buccal Pad of Fat for management of OAC.
Group II	A-PRF	patients were treated using A-PRF technique for management of OAC.
Group III	fibrin glue	patients were treated with Fibrin Glue for management of OAC.

Primary Outcome Measures

Name	Time	Method
o Recurrence	6 months	presence or absence

Secondary Outcome Measures

Name	Time	Method
pain, visual analog scale	4 weeks	0 no pain, 10 severe pain

Trial Locations

Locations (1)

October 6U; 🇪🇬 Cairo, Egypt