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临床试验/NCT01366781
NCT01366781已完成不适用

Effects of Varying Meal Size on Gut Hormone and Islet Hormone Secretion in Males Versus Females

Lund University2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2011年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
2
主要终点
Release of gut hormones

研究概览

简要总结

The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.

详细描述

In healthy males and females, meals with 511, 743 and 1034 kcal will be given orally. Samples will be taken during the following 300 min and gut hormones (glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1) will be determined along with insulin and glucagon levels.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Factorial
盲法
None

入排标准

年龄范围
20 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy status

排除标准

  • Liver disease
  • kidney disease
  • thyroid disease

结局指标

主要结局

Release of gut hormones

时间窗: 300 min

次要结局

  • Insulin secretion(300 min)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bo Ahren

Professor

Lund University

研究点 (2)

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