Effect of xantina oxidasi inhibition on left ventricular function and on energetic stores of the haert in patients affected by chronic cardiac insufficiency. - ND

Phase 1

• Conditions: patients affected by cardiac insufficiency; MedDRA version: 9.1Level: PTClassification code 10007554

• Registration Number: EUCTR2009-015958-38-IT
• Lead Sponsor: FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-09-15
• Last Update Posted: 26 October 2021

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

patients aged between 50 and 90 years old; FE < or equal to 40% documented by ecocardio; uricemia > or equal to 8 mg/die; cardiac insufficiency from about 6 months; steady basal therapy for at least 2 months; NYHA II-III class
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

diseases that may interfere with the study; enrollment in other clinical study;climateric women in hormonal therapy; instable angina or malignant heart block;untreated ipokaliemia; intollerance to allopurinolo; intake of drugs that may induce iperuricemia; patients unable to take part to the study and to underwent the tests

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified