Clinical Evaluation of Traditional Chinese Medicine Intervention for Unstable Angina Based on Bi-Directional Cohort Study

Not Applicable

• Conditions: nstable angina pectoris

• Registration Number: ITMCTR2024000023
• Lead Sponsor: The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Meet the diagnostic criteria for unstable angina pectoris of coronary heart disease;
2. Hospitalized more than two times in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from 2013 to May 2023, UA was treated with Western medicine or traditional Chinese medicine (including Chinese herbal decoction, oral Chinese patent medicine, and Chinese medicine injection) combined with western medicine during hospitalization.
3. Record at least one hospitalization in the three months before enrollment.

Exclusion Criteria

1. Patients with valvular heart disease, various types of cardiomyopathy, malignant arrhythmia, and NYHA functional classification III-IV heart failure;
2. Patients with untreated or uncontrolled hypertension (BP=180/100mmHg);
3. Patients diagnosed with severe brain tumors or traumatic brain diseases;
4. Patients with acute cerebrovascular disease that occurred in the past two weeks;
5. severe pulmonary dysfunction (PaO2 <60mmHg), severe primary diseases of the endocrine and hematopoietic system, moderate to severe hepatic dysfunction (transaminase levels exceeding the upper limit of normal 3 times) or renal dysfunction (eGFR less than 60/min/1.73m2), and high creatinine levels exceeding the normal value;
6. Patients with tumors;
7. Patients with mental illness;
8. Patients with unstable angina pectoris with complete revascularization (Means to bypass all vessels > 2.0mm in diameter with > 50% stenosis)

Study & Design

• Study Type: Observational study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Readmission density for cardiovascular related diseases;

Secondary Outcome Measures

Name	Time	Method
All-cause mortality;Major adverse cardiovascular events (MACE);Seattle Angina Questionnaire (SAQ) score values;