NCT02159001Unknown不适用
Efficacy and Cognitive Effects of Electroconvulsive Therapy in Clozapine-Resistant Schizophrenia
Niuvanniemi Hospital1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2014年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Positive and Negative Symptom Scale
研究概览
简要总结
Electroconvulsive therapy (ECT) is one of the oldest neuromodulation treatments still used in psychiatry. Only case reports and open label non-randomized studies have been published of ECT in clozapine-resistant schizophrenia patients. The purpose of this trial is to study the efficacy and cognitive effects of add-on ECT treatment (10-course) in schizophrenia patients taking clozapine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of schizophrenia or schizoaffective disorder
- •treatment-resistant to clozapine
- •age 18 - 64 years
- •capacity and willingness to give informed consent
排除标准
- •serious somatic illness
- •progressive neurological illness, recent brain damage or sequela of serious brain damage
- •ECT less than 3 months prior to this trial
结局指标
主要结局
Positive and Negative Symptom Scale
时间窗: 2 days
Positive and Negative Symptom Scale (PANSS) is assessed two days after ECT course
次要结局
未报告次要终点
研究者
研究点 (1)
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