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THE PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTION BETWEEN PROPOFOL AND KETAMINE WHEN GIVEN FOR SEDATION AFTER CARDIAC SURGERY IN THE INTENSIVE CARE UNIT.

Completed
Conditions
sedativum op IC na cardiochirurgische ingreep
eris geen sprake van een te bestuderen aandoening
Registration Number
NL-OMON34050
Lead Sponsor
eids Universitair Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
42
Inclusion Criteria

Scheduled for ventilation and sedation at the ICU post cardiac surgery.
Aged 18-80 years.
Being able to give written informed consent.

Exclusion Criteria

Unable to give written informed consent.
Increased intracranial pressure
Poor ventricular function
Epilepsy
Psychosis
Glaucoma
History of cerebrovascular incident < 1 year
Pregnancy
Documented or suspected soybean protein and/or drug allergy.
Morbid obesity (BMI > 35).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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