ISRCTN43596477Completed未知
Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure
niversity Hospital Basel (Switzerland)0 sites820 target enrollmentStarted: September 23, 2005Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 820
Study Overview
Brief Summary
- 2006 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/16644310 2. 2009 results in: http://www.ncbi.nlm.nih.gov/pubmed/19176440 3. 2011 results in: http://www.ncbi.nlm.nih.gov/pubmed/22067089 4. 2012 results in: http://www.ncbi.nlm.nih.gov/pubmed/22424011 5. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/24352403 6. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23384944 7. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23666681 8. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/24621800 9. 2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23657728 10. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25576682 11. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25981371 12. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26472682 13. 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/27503849 14. 2018 post hoc analysis in: http://www.ncbi.nlm.nih.gov/pubmed/29896315
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Heart failure patients aged greater than 60 years
- •2. New York Heart Association (NYHA) greater than or equal to II
- •3. CHF hospitalisation within last year
- •4. NT-BNP level greater than 800 pg/ml (greater than or equal to 75 years), 400 pg/ml (60 - 74 years)
Exclusion Criteria
- •1. Serum creatinine greater than 220 µmol/l
- •2. Valve disease needing surgery
- •3. Disease other than cardiovascular limiting life-expectancy less than 3 years
- •4. No informed consent
Investigators
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