Effects of aggressive lipid-lowering therapy on atherosclerosis and multi-lipoprotein profiling in patients with coronary artery disease

Not Applicable

• Conditions: Patients with coronary artery disease

• Registration Number: JPRN-UMIN000002507
• Lead Sponsor: agoya University Graduate School of Medicine

Brief Summary

We demonstrated that treatment with pitavastatin attenuated atherosclerotic plaque. This effect was associated with the level of HDL cholesterol, and was stronger in the absence of diabetes and metabolic syndrome in our ischemic heart disease patients.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-10-01
• Study Completion: 2012-03-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients who have suffered from stroke for the past three months. 2) Patients who have suffered from acute myocardial infarction for the past week. 3) Patients planning CABG in the study periods. 4) Patients planning addition or change of cilostazol in the study periods 5) Patients planning CAS in the study periods 6) Patients with active malignant tumor. 7) Patients with severe renal dysfunction. 8) Patients with severe hepatic dysfunction. 9) Patients with collagen disease. 10) Patients judged as being inappropriate for this study by investigators.

Study & Design

• Study Type: Interventional
• Study Design: Not specified