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Clinical Trials/NCT06355193
NCT06355193CompletedPhase 1

The Use of Isatidis Root and Forsythia Oral Liquid for the Treatment of Mild Cases of COVID-19: A Trial Clinical Study

Central South University1 site in 1 country253 target enrollmentStarted: November 1, 2022Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Phase 1
Status
Completed
Sponsor
Enrollment
253
Locations
1
Primary Endpoint
Treatment and symptomatic improvement effects of LGLQ

Study Overview

Brief Summary

This study has significant implications for research, as it provides a basis for further studies on the antiviral effects of LGLQ Oral Liquid, encouraging more extensive clinical studies in larger populations and diverse age groups to validate these findings. For medical practice, the findings suggest that LGLQ can be considered an alternative treatment option for mild cases of COVID-19, especially in managing symptoms like fatigue, potentially broadening the range of effective treatments available to healthcare practitioners. In terms of policy, the demonstrated efficacy of LGLQ could lead to its inclusion in treatment guidelines for COVID-19 and other viral infections, fostering a more integrated approach combining Western medicine and Traditional Chinese Medicine in the global fight against pandemics. The insights from this study might prompt health policymakers to reassess the potential of herbal formulations in managing and treating infectious diseases and consider them in the development of future healthcare strategies and policies.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • the diagnosis of SARS-Cov-2 infection confirmed by quantitative polymerase chain reaction (qPCR) test
  • aged 18 years or older
  • patients received more than 2 doses of SARS-Cov-2 vaccine
  • asymptomatic or mild at the time of hospitalization

Exclusion Criteria

  • patients with malignant diseases, autoimmune diseases, liver and kidney diseases, blood diseases, neurological diseases, endocrine diseases and other serious diseases may affect the patient's participation in the trial or affect the results of the study
  • pregnant women, lactating mothers; allergic conditions
  • allergic to the known components of the drug
  • patients vaccinated with vaccines less than 1 shot
  • Patient does not agree to participate in this study

Arms & Interventions

LGLQ group

Experimental

Intervention: Langenlianqiao (Drug)

LHQW group

Experimental

Intervention: LianhuaQingWen (Drug)

placebo control group

Placebo Comparator

Intervention: placebo control group (Other)

Outcomes

Primary Outcomes

Treatment and symptomatic improvement effects of LGLQ

Time Frame: 1 month

LGLQ and LHQW were able to significantly reduce the duration of infection with novel coronaviruses

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Central South University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mi Zhou

Investigator

Central South University

Study Sites (1)

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