The Use of Isatidis Root and Forsythia Oral Liquid for the Treatment of Mild Cases of COVID-19: A Trial Clinical Study
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Enrollment
- 253
- Locations
- 1
- Primary Endpoint
- Treatment and symptomatic improvement effects of LGLQ
Study Overview
Brief Summary
This study has significant implications for research, as it provides a basis for further studies on the antiviral effects of LGLQ Oral Liquid, encouraging more extensive clinical studies in larger populations and diverse age groups to validate these findings. For medical practice, the findings suggest that LGLQ can be considered an alternative treatment option for mild cases of COVID-19, especially in managing symptoms like fatigue, potentially broadening the range of effective treatments available to healthcare practitioners. In terms of policy, the demonstrated efficacy of LGLQ could lead to its inclusion in treatment guidelines for COVID-19 and other viral infections, fostering a more integrated approach combining Western medicine and Traditional Chinese Medicine in the global fight against pandemics. The insights from this study might prompt health policymakers to reassess the potential of herbal formulations in managing and treating infectious diseases and consider them in the development of future healthcare strategies and policies.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •the diagnosis of SARS-Cov-2 infection confirmed by quantitative polymerase chain reaction (qPCR) test
- •aged 18 years or older
- •patients received more than 2 doses of SARS-Cov-2 vaccine
- •asymptomatic or mild at the time of hospitalization
Exclusion Criteria
- •patients with malignant diseases, autoimmune diseases, liver and kidney diseases, blood diseases, neurological diseases, endocrine diseases and other serious diseases may affect the patient's participation in the trial or affect the results of the study
- •pregnant women, lactating mothers; allergic conditions
- •allergic to the known components of the drug
- •patients vaccinated with vaccines less than 1 shot
- •Patient does not agree to participate in this study
Arms & Interventions
LGLQ group
Intervention: Langenlianqiao (Drug)
LHQW group
Intervention: LianhuaQingWen (Drug)
placebo control group
Intervention: placebo control group (Other)
Outcomes
Primary Outcomes
Treatment and symptomatic improvement effects of LGLQ
Time Frame: 1 month
LGLQ and LHQW were able to significantly reduce the duration of infection with novel coronaviruses
Secondary Outcomes
No secondary outcomes reported
Investigators
Mi Zhou
Investigator
Central South University
