Dose-dependent Identification of Unique Biomarkers
- Conditions
- Healthy
- Registration Number
- NCT05600348
- Lead Sponsor
- San Diego State University
- Brief Summary
The purpose of the research is to assess the dose-dependent impacts of the consumption of fresh pork on blood-borne metabolites (markers) following the controlled feeding of pork
- Detailed Description
Eligible participants will follow 3 randomly ordered 4-week feeding periods varying only with the consumption of 0, 3 or 6 oz of pork or a 50:50 blend of chicken and beef (6, 3 and 0 oz for respective trials to ensure similar total poultry/meat intake among trials).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
- generally healthy (i.e., an absence of diagnosed chronic illnesses and inborn metabolic disorders)
- Age 18-65
- all races
- both sexes
- willingness to comply with the research diet requirements
- special dietary needs (e.g., vegetarianism, gluten-free, etc.)
- use of medication known to influence metabolism
- smoking
- substance use
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Metabolic biomarker discovery 4 weeks Biomolecules detected through metabolomic profiling that will result in discovery of a metabolic signature for pork intake
- Secondary Outcome Measures
Name Time Method LDL-Cholesterol 4 weeks LDL-Cholesterol
Interleukin-6 4 weeks Interleukin-6
Total Cholesterol 4 weeks Total Cholesterol
HDL Cholesterol 4 weeks HDL Cholesterol
C-Reactive Protein 4 weeks C-Reactive Protein
Fasted Glucose 4 weeks Fasted Glucose
Insulin 4 weeks Insulin
Blood Pressure 4 weeks Systolic and Diastolic
Triglycerides 4 weeks Triglycerides
Body Composition 4 weeks Weight measured via scalre, body fat% muscle mass as measured via DEXA
Trial Locations
- Locations (1)
School of Exercise and Nutritional Sciences
🇺🇸San Diego, California, United States
School of Exercise and Nutritional Sciences🇺🇸San Diego, California, United States