Skip to main content
Clinical Trials/NCT04524065
NCT04524065
Recruiting
N/A

Effectiveness and Safety of an Early Mobilization Protocol in a Pediatric Intensive Care Unit

Samsung Medical Center1 site in 1 country142 target enrollmentOctober 27, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Critical Illness
Sponsor
Samsung Medical Center
Enrollment
142
Locations
1
Primary Endpoint
Change From Baseline Functional Status Score (FSS) at Post Test(PICU discharge)
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study evaluates the safety and effectiveness of an early rehabilitation program in a pediatric intensive care unit (PICU). Half of the participants will receive intensive and frequent an early mobilization program and others will receive conservative mobilization program.

Detailed Description

The 14 early rehabilitation sessions(10=physical therapy, 4=occupational therapy) occurred per week over a 2-week period (excluding weekends) in the early rehabilitation group for 15 minutes each. The control group received 2 sessions(physical therapy) per week over a 2-week period for 10 minutes each.

Registry
clinicaltrials.gov
Start Date
October 27, 2020
End Date
December 30, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jeong Yi Kwon

Professor

Samsung Medical Center

Eligibility Criteria

Inclusion Criteria

  • Children admitted to the PICU due to critical illness
  • Children aged 1-18 years

Exclusion Criteria

  • Increased intracranial pressure(ICP)
  • History of brain surgery
  • Children with fracture
  • Admitted to the participating PICU ≤ 3 days
  • Children with suspected brain death

Outcomes

Primary Outcomes

Change From Baseline Functional Status Score (FSS) at Post Test(PICU discharge)

Time Frame: Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da

Functional Status Scale (FSS) domains of functioning included mental status, sensory functioning, communication, motor functioning, feeding, and respiratory status, categorized from normal (score = 1) to very severe dysfunction (score = 5). FSS scores ranged from 6 to 30.

Secondary Outcomes

  • Hospital length of stay (days)(From Baseline to hospital discharge)
  • Canadian Occupational Performance Measure (COPM)(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • The Pediatric Evaluation of Disability Inventory-Computer Adaptive Test(PEDI-CAT)(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • The Pediatric Risk of Mortality III (PRISM III)(At PICU admission)
  • Muscle strength measures of elbow flexor and knee extensor obtained with a hand-held dynamometer(MicroFET2).(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • Pediatric Sequential Organ Failure Assessment(pSOFA)(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • Duration of mechanical ventilation (days)(Perioid between intubation and extubation of mechanical ventilation)
  • PICU length of stay (days)(From PICU admission to discharge)
  • Safety index(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • Number of patients discharged from the hospital to a place other than home(At hospital discharge)
  • Change From post-test(PICU discharge) Pediatric Quality of Life Inventory version 4.0 (PedsQL 4.0) at follow-up test(2 months)(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)
  • Change From baseline The State-Trait Anxiety Inventory (STAI) at follow-up test(2 months)(Evaluation is conducted at two time points. At baseline (T0), assessment is carried out for within 7 days after admission to the PICU. For T1, assessment occurs within 7 days after PICU discharge or, for patients unable to be discharged, at the 30-da)

Study Sites (1)

Loading locations...

Similar Trials