MedPath

Safety and Efficacy of an Early Rehabilitation Program in Surgical Intensive Care Unit

Not Applicable
Completed
Conditions
ICU-acquired Weakness
Interventions
Behavioral: Early rehabilitation program
Registration Number
NCT03055949
Lead Sponsor
Asan Medical Center
Brief Summary

The purpose of this study is to determine whether an early rehabilitation program in surgical intensive care unit is safe and effective in preventing critical care illness and intensive care unit acquired weakness.

Detailed Description

Due to the complications like intensive care unit-acquired weakness, critical illness polyneuropathy and neuropsychiatric disease of critical care, many organizations focus on rehabilitation in critically ill patients' management. Despite the good outcomes from papers, there are debatable issues of method, safety and efficacy of rehabilitation. The investigators developed an early rehabilitation program (ERP) in our surgical ICU management and assessed safety and efficacy of it.

The ERP started in November 2014 in our 14-bed surgical ICU in Asan Medical Center. The investigators focused on early and 5-step rehabilitation program for patients who were admitted to SICU for at least 3 days. The investigators enrolled 69 patients (pre-ERP group) for 6 months before November 2014 and 62 patients (post-ERP group) for 6 months 1 year after the ERP started. The main measures were safety issues, delirium days, 28-d ventilator free-days, 28-d ICU free-days, hospital length of stay (LOS), ICU mortality, in-hospital mortality and 1 year mortality.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
131
Inclusion Criteria
  • patients who were admitted in SICU for at least 3 days
Read More
Exclusion Criteria
  • readmission to SICU within current hospitalization open abdomen wound patients major bone fracture patients brain death patients active bleeding patients increased intra-cranial pressure patients paraplegic patients patients or their guardians did not agree with the ERP doctor's decision (Deconditioning patients, Procedure)
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
post-ERPEarly rehabilitation programA group of the surgical ICU patients who had an early rehabilitation program (ERP) within SICU care
Primary Outcome Measures
NameTimeMethod
28-day Ventilator-free days (days)up to 28-day

Patients who died during the study were assigned scores of 0 for 28-day ventilator-free days.

28-day ICU-free days (days)up to 28-day

Patients who died during the study were assigned scores of 0 for 28-day ICU-free days

Secondary Outcome Measures
NameTimeMethod
Time to start rehabilitation from ICU admission (days)up to 2 weeks
ICU delirium days (days)up to 4 weeks
Total rehabilitation days within ICU days (days)up to 4 weeks
ICU readmission rate (%)up to 24 weeks
ICU mortality rate (%)up to 24 weeks
in-hospital mortality rate (%)up to 24 weeks
1 year mortality rate (%)1 year follow up from ICU admission
© Copyright 2025. All Rights Reserved by MedPath