The tissue effect of argon plasma coagulation on the resected human gastric mucosa
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0001003
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Without submucosal injection, the incidence of damaging the muscularis propria increased as the power and duration increased. Tissue damage in the injection group was mostly confined to the submucosa, even in the high-power setting. In the injection group, ablations at 40 W for 20 s, 60 W for 15 s, and 80 W for 15 or 20 s produced success rates =80%. In the control group, ablations at 60 W for 10 s, and 80 W for 5 or 10 s produced success rates =80%. The optimal energy levels to achieve complete mucosal and submucosal necrosis without damaging the muscularis propria were 800-1,600 and 600-800 J in the injection and controls, respectively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Patient with total gastrectomy due to gatric cancer located at the middle and high third of stomach
1. Gastric cancer which is located at the lower third or antral part of stomach
2. Gastric cancer which is indicated for endoscopic resection
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depth of ablation
- Secondary Outcome Measures
Name Time Method Depth of ablation in proper muscle