跳至主要内容
临床试验/CTRI/2025/07/091962
CTRI/2025/07/091962尚未招募2/3 期

A comparative clinical study to evaluate the efficacy of vachadi choorna and kushmandadi choorna in vishada depression

Dr Shilpa1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年11月1日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Effect of Kushmandadi Choorna and Vachadi Choorna on physical and psychological symptoms of Vishada

研究概览

简要总结

NEED FOR THE STUDY•          Manas is the chief component responsible for perceiving good mental health which is a sign of good health mentioned in Sushruta Samhita.   Charaka has quoted ‘Vishado Rogavardhananam’ i.e. Vishada is the foremost factor in worsening the disease condition. The explanation of Vishada found in various references when compared to depression appear similar, so Vishada can be corelated with depression.  Depression is a state where person feel sad, hopeless, worthless, pessimistic and guilty

•      According to WHO an estimated 3.8% of the population experience depression, including 5% of adults (4% among men and 6% among women), 5.7% of adults older than 60 years. Approximately 280 million people in the world have depression.There is Manobudhyadi Vibramsha in Vishada as in Unmada hence Samanya Unmada Chikitsa can be used based on the understanding of the Dosha predominance.  Vachadi Choorna explained by Bhavaprakasha in Unmada Chikitsa, is Kapha Vatahara, Medhya, Vatanulomaka and Ojasya. As Vata is the controller of mind, normalcy of Vata is essential for Vatajananatmaja Vikara like Vishada.

•        Kushmandadi Choorna is also explained by Bhavaprakasha in context of Unmada Chikitsa whichis Kapha Vatahara, Balya and indicated in Manasa Vikara. Both Choorna in general contains Kusta Choorna which is Teekshna and Kapha Vatahara.

•        As Vishada is a condition in which body and mind is affected and the qualities of both the Choorna can provide solution by attacking disturbed Vata and Kapha and improving the Buddhi and Medha helping in balance of psychological state of the individual.

•        So this study is aimed to compare the efficacy of both Vachadi Choorna and Kushmandadi Choorna in Vishada.

REVIEW OF LITERATURE

  • Bhagavadgeeta mentioned about Vishada Lakshanas in Arjuna’s extended period of despondency during the war (cha.1/27-30).
  • Acharya Charaka while describing Vataja Nanatmaja Vikara.(cha.su.20/11) has mentionedVishada is thedisease caused by Vata.
  • *Vishado Rogavardhananam-*While explaining Agrya Sangraha mentioned Vishada is the formost factor in worsening the disease condition. (cha.su 25/40).
  • Acharya Charaka in Vimana Sthana 4/8 while explaining Anumanagamya Bhavas mentioned ‘Bhayam Vishadena;Dhairyam Avishadena’ means understanding the feeling of fear in a person by seeing his depression state or behaviour and also strength of one’s mind can be assessed by ability to face the adversities without fear.
  • Acharya Sushruta mentioned Vishada as one among Manasa Roga(Su.su.1/33). Asiddhibhayat Vivideshu Karmasu Sadhoapravratti Vishada’.(Dalhana commentary on Su su 1/24)
  • Asiddhibhayat Vivideshu Karmasu Sadhoapravritti Vishada’.(Dalhana commentary on Su.su.1/24)
  • Vakkayachitta Avasadaha Vishadaha ( Su. Kalp. 3/21. Dalhana)
  • Acharya Vagbhata explains that due to affliction of Dukha the person mind may get shield with Rajoguna or Tamoguna causing Vishada as - ‘Vishannatvam Dukkitatvam’ (A.H Arunadatta 2/17)
  • Drug Review- *Bhavaprakasha Chikitsa Sthana Unmada Chikitsa -22/33**Vachadi Choorna –  Vacha, Kusta.*Kushmandadi Choorna -  Kushmanda Beeja , Kusta.

 AIMS AND OBJECTIVES OF THE STUDYAIM

·       To find a better alternative and cost effective treatment in the managementof Vishada.

OBJECTIVES

·       To know the effect of Kushmandadi Choorna and Vachadi Choorna on physical and psychological symptoms of Vishada.

·       To compare the efficacy of  Vachadi Choorna and Kushmandadi Choorna in the management of  Vishada

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
16.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients diagnosed as per the criteria for mild and moderate depression as per ICD-
  • Age between 16 to 60 years.

排除标准

  • Patients with other psychiatric disorders Patients with systemic illness Patients with major depression Pregnant women/lactating women.

结局指标

主要结局

Effect of Kushmandadi Choorna and Vachadi Choorna on physical and psychological symptoms of Vishada

时间窗: 45 days

次要结局

  • Find a better alternative and cost effective treatment in the management of Vishada(45 days)

研究者

发起方
Dr Shilpa
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Shilpa

Alvas Ayurveda Medical College And Hospital

研究点 (1)

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