High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Very Premature Infants: a Prospective Observational Study
Not Applicable
Completed
- Conditions
- Premature; Infant
- Interventions
- Device: High-Flow Nasal Cannula
- Registration Number
- NCT06458582
- Lead Sponsor
- Charles University, Czech Republic
- Brief Summary
A prospective observational study evaluates the safety and efficacy of using High-Flow Nasal Cannula to stabilize very preterm infants immediately after birth. Following placental transfusion, high flow nasal cannula at 8 l/min is administered along with intermittent tactile stimulation. Criteria for switching to other interventions like continuous positive airway pressure or positive pressure ventilation are set for cases of persistent bradycardia or low SpO2.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
- Preterm infants born between 28+0 and 31+6 gestational weeks were enrolled in the study after obtaining parental informed consent.
Exclusion Criteria
- Infants with congenital malformations, previable rupture of membranes, and acute intrauterine hypoxia.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description High-flow-nasal-cannula High-Flow Nasal Cannula In this study, very preterm infants receive High-Flow Nasal Cannula therapy immediately after birth. The intervention includes placental transfusion, followed by administering High-Flow Nasal Cannula at a flow rate of 8 l/min along with intermittent tactile stimulation. Criteria for switching to Continuous Positive Airway Pressure or Positive Pressure Ventilation are established for cases of persistent bradycardia or low SpO2.
- Primary Outcome Measures
Name Time Method HFNC slabilization 10 minutes after delivery Number of infants who were stabilized after birth on high flow nasal cannula exclusively without any other use of artificial external pressures.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Charles University in Prague
🇨🇿Praha, Czech, Czechia