HFNC and Prone Positioning in Awake Patients With Severe COVID-19
Completed
- Conditions
- Hypoxemic Respiratory Failure
- Interventions
- Procedure: prone position
- Registration Number
- NCT04982341
- Lead Sponsor
- Hôpital Universitaire Fattouma Bourguiba
- Brief Summary
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.
- Detailed Description
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.
All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC.
Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure
Exclusion Criteria
- patients already intubated at admission or those requiring immediate intubation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description HFNC/prone prone position awake patients with COVID-19 and severe acute respiratory failure receiving HFNC in prone position
- Primary Outcome Measures
Name Time Method Number of patients without intubation through study completion, an average of 28 days successful oxygenation without intubation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU F.Bourguiba
🇹🇳Monastir, Tunisia