MedPath

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Phase 2
Recruiting
Conditions
Unresectable Acral Lentiginous Melanoma
Clinical Stage IV Cutaneous Melanoma AJCC v8
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Unresectable Melanoma
Unresectable Mucosal Melanoma
Clinical Stage III Cutaneous Melanoma AJCC v8
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
Pathologic Stage IIID Cutaneous Melanoma AJCC v8
Advanced Melanoma
Melanoma of Unknown Primary
Interventions
Biological: Nivolumab
Biological: Ipilimumab
Other: Patient Observation
Biological: Pembrolizumab
Registration Number
NCT04462406
Lead Sponsor
ECOG-ACRIN Cancer Research Group
Brief Summary

This phase II trial investigates how well biomarkers on PET/CT imaging drive early discontinuation of anti-PD-1 therapy in patients with stage IIIB-IV melanoma that cannot be removed by surgery (unresectable). Anti-PD-1 therapy has become a standard therapy option for patients with unresectable melanoma. This trial is being done to determine if doctors can safely shorten the use of standard of care anti-PD1 therapy for melanoma by using biomarkers seen on PET/CT imaging and tumor biopsy.

Detailed Description

PRIMARY OBJECTIVE:

I. To determine the 12 month event free survival (EFS) rate following discontinuation of anti-PD-1 therapy in patients with disease control and negative fludeoxyglucose F-18 (FDG)- positron emission tomography (PET)/computed tomography (CT) scan or biopsy for residual disease after 12 months of anti-PD-1 therapy (Arm A).

SECONDARY OBJECTIVES:

I. To determine rates of pathologic response in patients with tumor biopsies where positive hypermetabolic activity was present on FDG-PET/CT scan after 12 months of anti-PD-1 therapy (Arm B).

II. To determine the overall 24 month EFS. III. To determine overall survival from start of anti-PD-1 therapy. IV. To determine percentage for patients who remain on treatment beyond 12 months because of positive FDG-PET/CT scan and positive biopsy for residual disease (or unable to obtain a biopsy).

V. To determine incidence rates of treatment-related adverse events beyond 12 months from start of treatment in patients who discontinue anti-PD-1 therapy at 12 months and in patients who continue anti-PD-1 therapy beyond 12 months (Arm A versus \[vs.\] Arm B).

EXPLORATORY OBJECTIVES:

I. To assess agreement in determining FDG-PET/CT positivity between the local site read and central review.

II. To determine if metabolic response on serial FDG-PET/CT from pre-therapy to 12 months of anti-PD-1 therapy, as determined centrally by various criteria, is associated with EFS.

III. To determine if metabolic response on serial FDG-PET/CT from 12 to 24 months after start of anti-PD-1 therapy, as determined centrally by various criteria, is associated with EFS.

BIOMARKER OBJECTIVE:

I. To bank tumor samples and peripheral blood for future biomarker studies.

OUTLINE: Patients continue their standard of care anti-PD-1 therapy and are then assigned to 1 of 2 arms.

STANDARD OF CARE: Treatment may consist of the following regimens: 1) nivolumab intravenously (IV) over 30 minutes every 2 weeks (Q2W) or every 4 weeks (Q4W); 2) pembrolizumab IV over 30 minutes every 3 weeks (Q3W) or every 6 weeks (Q6W); 3) nivolumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by nivolumab IV over 30 minutes Q2W or Q4W; or 4) pembrolizumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by pembrolizumab IV over 30 minutes Q3W or Q6W. Treatment continues until 52 weeks from start of standard of care anti-PD-1 therapy in the absence of disease progression or unacceptable toxicity.

ARM A: Patients with a negative FDG-PET/CT scan or a positive FDG-PET/CT scan but with a negative biopsy for viable tumor discontinue the anti-PD-1 therapy and undergo active surveillance.

ARM B: Patients with a positive FDG-PET/CT scan and positive biopsy for viable tumor or a positive FDG-PET/CT scan and biopsy not performed continue their standard of care anti-PD-1 therapy for 12 months in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up through week 97 and then every 3 months for up to 5 years.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
150
Inclusion Criteria
  • STEP 0 PRE-REGISTRATION INCLUSION CRITERIA

  • Patient must have active advanced melanoma, defined as unresectable stage IIIB-IV by American Joint Committee on Cancer (AJCC) 8th edition

  • Patient must have melanoma originating from cutaneous, acral-lentiginous, or mucosal primary sites. Patients with melanoma of unknown primary site are eligible. Patients must not have melanoma from an ocular primary site

  • Patient must have had measurable disease by immune related Response Evaluation Criteria in Solid Tumors (imRECIST) prior to start of initial anti-PD-1 therapy

  • Patient must be actively receiving standard of care anti-PD-1 therapy, currently be 52 weeks (+/- 2 weeks) from start of anti-PD-1 therapy, and have not experienced a toxicity that prevents them from continuing on therapy. Permitted systemic anti-PD-1 therapy regimens include:

    • Nivolumab 240 mg IV every (Q)2weeks or 480 mg IV Q4weeks
    • Pembrolizumab 200 mg IV Q3weeks or 400 mg IV Q6weeks
    • Nivolumab 1 mg/kg plus ipilimumab 3 mg/kg IV Q3weeks induction x 4 doses, followed by nivolumab 240 mg IV Q2weeks or 480 mg IV Q4weeks maintenance
    • Nivolumab 3 mg/kg plus Ipilimumab 1 mg/kg IV Q3weeks induction x 4 doses, followed by nivolumab 240 mg IV Q2weeks or 480 mg IV Q4weeks maintenance
    • Pembrolizumab 2 mg/kg (or 200 mg flat dose) plus Ipilimumab 1 mg/kg IV Q3weeks induction x 4 doses, followed by pembrolizumab 200 mg IV Q3weeks or 400 mg IV Q6weeks maintenance
  • Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2

  • Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial. Patients with detectable viral loads are excluded as it is unclear if these patients have a low risk of melanoma progression off anti-PD-1 treatment

  • For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated

  • Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load

  • Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial

  • Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better

  • Patient must have experienced complete response, partial response, or stable disease on restaging CT scans by imRECIST that is maintained on restaging scans obtained at week 52 (+/- 2 weeks) from start of initial anti-PD-1 therapy

  • Patient must have completed an FDG-PET/CT scan at week 52 (+/- 2 weeks) from start of initial anti-PD-1 therapy

    • Patients with PET/CT positive for hypermetabolic lesions: If a core needle, punch or excisional biopsy and pathological review of a representative lesion was not performed prior to pre-registration (Step 0) must either:

      • Be amenable to undergo a biopsy. Patient must not be on anticoagulation therapy or, if on anti-coagulation therapy, patient must be able to hold treatment for a biopsy procedure (core needle, punch or excisional biopsy). Anti-coagulation therapy is defined as low molecular weight heparin, warfarin, factor Xa inhibitor, or direct thrombin inhibitor
      • Have documentation of inability to perform the biopsy due to feasibility or safety concerns
  • Leukocytes >= 3,000/mcL (obtained =< 4 weeks prior to protocol registration)

  • Absolute neutrophil count >= 1,500/mcL (obtained =< 4 weeks prior to protocol registration)

  • Platelets >= 100,000/mcL (obtained =< 4 weeks prior to protocol registration)

  • Total bilirubin =< institutional upper limit of normal (ULN) (patients with history of Gilbert's syndrome are permitted to have a total bilirubin > 1.5 x institutional ULN) (obtained =< 4 weeks prior to protocol registration)

  • Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN (obtained =< 4 weeks prior to protocol registration)

  • Creatinine =< 1.5 x institutional ULN (obtained =< 4 weeks prior to protocol registration)

  • STEP 1 REGISTRATION INCLUSION CRITERIA

  • Patient met all eligibility criteria outlined above

  • Patient must register to Step 1 within 4 weeks of registration to Step 0

  • Patients must meet one of the following criteria:

    • Patient had no positive hypermetabolic lesions on the week 52 FDG-PET/CT.

    • Patients with positive hypermetabolic lesion(s) on the week 52 FDG-PET/CT (positive hypermetabolic = standard uptake volume [SUV] > pooled mediastinal blood), one of the following must have occurred:

      • A representative lesion was biopsied (core needle, punch or excisional biopsy) within 14 days of registration to Step 0 and subsequent pathology review performed to determine the presence or absence of viable tumor
      • Documentation is present that the patient is not able to undergo biopsy of a hypermetabolic lesion due to feasibility or safety concerns, i.e., the lesion location that is not amenable to biopsy
Exclusion Criteria
  • STEP 0 PRE-REGISTRATION EXCLUSION CRITERIA
  • Patient must not be receiving concurrent anti-tumor therapies in addition to the standard of care anti-PD-1 regimens. Patients who are receiving bisphosphonates and RANKL inhibitors for management of bone metastases are eligible
  • Patient must not have brain metastases
  • Women must not be pregnant or breast-feeding due to potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the anti-PD-1 regimens being used. All females of childbearing potential must have a blood test or urine study within 14 days prior to registration to rule out pregnancy. A female of childbearing potential is defined as any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
  • Women of childbearing potential and sexually active males must not conceive or father children by using accepted and effective method(s) of contraception or by abstaining from sexual intercourse from the time of study registration and continuing until at least 5 months after the last dose of anti-PD-1 treatment for female patients and for at least 7 months after the last dose of anti-PD-1 treatment for male patients who are sexually active with a women of childbearing potential (WOCBP)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SEQUENTIAL
Arm && Interventions
GroupInterventionDescription
Arm B (nivolumab, pembrolizumab, ipilimumab)PembrolizumabPatients with a positive FDG-PET/CT scan and positive biopsy for viable tumor or a positive FDG-PET/CT scan and biopsy not performed continue their standard of care anti-PD-1 therapy for 12 months in the absence of disease progression or unacceptable toxicity.
Arm B (nivolumab, pembrolizumab, ipilimumab)NivolumabPatients with a positive FDG-PET/CT scan and positive biopsy for viable tumor or a positive FDG-PET/CT scan and biopsy not performed continue their standard of care anti-PD-1 therapy for 12 months in the absence of disease progression or unacceptable toxicity.
Standard of Care (nivolumab, pembrolizumab, ipilimumab)IpilimumabPatients continue their standard of care anti-PD-1 therapy. Treatment may consist of the following regimens: 1) nivolumab IV over 30 minutes Q2W or Q4W; 2) pembrolizumab IV over 30 minutes Q3W or Q6W; 3) nivolumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by nivolumab IV over 30 minutes Q2W or Q4W; or 4) pembrolizumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by pembrolizumab IV over 30 minutes Q3W or Q6W. Treatment continues until 52 weeks from start of standard of care anti-PD-1 therapy in the absence of disease progression or unacceptable toxicity.
Arm A (active surveillance)Patient ObservationPatients with a negative FDG-PET/CT scan or a positive FDG-PET/CT scan but with a negative biopsy for viable tumor discontinue the anti-PD-1 therapy and undergo active surveillance.
Standard of Care (nivolumab, pembrolizumab, ipilimumab)NivolumabPatients continue their standard of care anti-PD-1 therapy. Treatment may consist of the following regimens: 1) nivolumab IV over 30 minutes Q2W or Q4W; 2) pembrolizumab IV over 30 minutes Q3W or Q6W; 3) nivolumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by nivolumab IV over 30 minutes Q2W or Q4W; or 4) pembrolizumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by pembrolizumab IV over 30 minutes Q3W or Q6W. Treatment continues until 52 weeks from start of standard of care anti-PD-1 therapy in the absence of disease progression or unacceptable toxicity.
Standard of Care (nivolumab, pembrolizumab, ipilimumab)PembrolizumabPatients continue their standard of care anti-PD-1 therapy. Treatment may consist of the following regimens: 1) nivolumab IV over 30 minutes Q2W or Q4W; 2) pembrolizumab IV over 30 minutes Q3W or Q6W; 3) nivolumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by nivolumab IV over 30 minutes Q2W or Q4W; or 4) pembrolizumab IV over 30 minutes and ipilimumab IV Q3W for 4 doses followed by pembrolizumab IV over 30 minutes Q3W or Q6W. Treatment continues until 52 weeks from start of standard of care anti-PD-1 therapy in the absence of disease progression or unacceptable toxicity.
Primary Outcome Measures
NameTimeMethod
Event free survival (EFS) rate (Arm A)At 12 months

Event is defined as recurrence, progression or melanoma-specific death. The distribution of EFS will be evaluated using the method of Kaplan-Meier.

Secondary Outcome Measures
NameTimeMethod
Incidence rates of treatment-related adverse events -12 months from start of treatment in patients who discontinue anti-PD-1 therapy at 12 months (Arm A) and in patients who continue anti-PD-1 therapy beyond 12 months (Arm B)Up to 5 years

95% CIs will be provided for all estimated rates.

Rates of pathologic response (Arm B)After 12 months of anti-PD-1 therapy

Will be defined as the absence of residual viable melanoma in the resected metastasis site as assessed on local pathology review. Pathologic response rate will be estimated in patients with tumor biopsies where positive hypermetabolic activity was present on FDG-PET/CT scan after 12 month of anti-PD-1 therapy on Arm B. 95% confidence intervals (CIs) will be provided for all estimated rates.

Overall survivalAt 24 months

Overall 24 month EFS for patients in Arm B will be summarized.

EFSAt 24 months

The distribution of EFS will be evaluated using the method of Kaplan-Meier.

Percentage of patients who remain on treatment beyond 12 monthsUp to 5 years

Will determine the percentage of patients who remain on treatment beyond 12 months because of positive fludeoxyglucose F-18 (FDG)-positron emission tomography (PET)/computed tomography (CT) scan and positive biopsy for residual disease (or unable to obtain a biopsy).

Trial Locations

Locations (481)

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

Great Lakes Cancer Management Specialists-Doctors Park

🇺🇸

East China Township, Michigan, United States

Bronson Battle Creek

🇺🇸

Battle Creek, Michigan, United States

Hickman Cancer Center

🇺🇸

Adrian, Michigan, United States

Michigan Breast Specialists-Macomb Township

🇺🇸

Macomb, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

🇺🇸

Livonia, Michigan, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

🇺🇸

Grand Island, Nebraska, United States

Toledo Clinic Cancer Centers-Toledo

🇺🇸

Toledo, Ohio, United States

Spartanburg Medical Center

🇺🇸

Spartanburg, South Carolina, United States

Spartanburg Medical Center - Mary Black Campus

🇺🇸

Spartanburg, South Carolina, United States

UW Cancer Center at ProHealth Care

🇺🇸

Waukesha, Wisconsin, United States

University of Illinois

🇺🇸

Chicago, Illinois, United States

The Angeles Clinic and Research Institute - West Los Angeles Office

🇺🇸

Los Angeles, California, United States

Ohio State University Comprehensive Cancer Center

🇺🇸

Columbus, Ohio, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

UM Sylvester Comprehensive Cancer Center at Kendall

🇺🇸

Miami, Florida, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

Mobile Infirmary Medical Center

🇺🇸

Mobile, Alabama, United States

Thomas Hospital

🇺🇸

Fairhope, Alabama, United States

Kaiser Permanente-Deer Valley Medical Center

🇺🇸

Antioch, California, United States

Kaiser Permanente Dublin

🇺🇸

Dublin, California, United States

Mercy Cancer Center - Elk Grove

🇺🇸

Elk Grove, California, United States

Mercy Cancer Center - Carmichael

🇺🇸

Carmichael, California, United States

Mercy San Juan Medical Center

🇺🇸

Carmichael, California, United States

Kaiser Permanente-Fremont

🇺🇸

Fremont, California, United States

Fresno Cancer Center

🇺🇸

Fresno, California, United States

Kaiser Permanente-Fresno

🇺🇸

Fresno, California, United States

Mercy Cancer Center

🇺🇸

Merced, California, United States

Kaiser Permanente Oakland-Broadway

🇺🇸

Oakland, California, United States

Kaiser Permanente-Oakland

🇺🇸

Oakland, California, United States

Kaiser Permanente-Modesto

🇺🇸

Modesto, California, United States

Kaiser Permanente-Rancho Cordova Cancer Center

🇺🇸

Rancho Cordova, California, United States

Kaiser Permanente-Richmond

🇺🇸

Richmond, California, United States

The Permanente Medical Group-Roseville Radiation Oncology

🇺🇸

Roseville, California, United States

Rohnert Park Cancer Center

🇺🇸

Rohnert Park, California, United States

Kaiser Permanente Cancer Treatment Center

🇺🇸

South San Francisco, California, United States

Memorial Hospital of Carbondale

🇺🇸

Carbondale, Illinois, United States

Woodland Memorial Hospital

🇺🇸

Woodland, California, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

HSHS Saint Elizabeth's Hospital

🇺🇸

O'Fallon, Illinois, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Edward Hospital/Cancer Center?Plainfield

🇺🇸

Plainfield, Illinois, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

McFarland Clinic - Ames

🇺🇸

Ames, Iowa, United States

Illinois CancerCare - Washington

🇺🇸

Washington, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Mission Cancer and Blood - Ankeny

🇺🇸

Ankeny, Iowa, United States

McFarland Clinic - Boone

🇺🇸

Boone, Iowa, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Mission Cancer and Blood - West Des Moines

🇺🇸

Clive, Iowa, United States

McFarland Clinic - Trinity Cancer Center

🇺🇸

Fort Dodge, Iowa, United States

Trinity Regional Medical Center

🇺🇸

Fort Dodge, Iowa, United States

McFarland Clinic - Jefferson

🇺🇸

Jefferson, Iowa, United States

McFarland Clinic - Marshalltown

🇺🇸

Marshalltown, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Saint Joseph Mount Sterling

🇺🇸

Mount Sterling, Kentucky, United States

Southeast Cancer Center

🇺🇸

Cape Girardeau, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Siteman Cancer Center at West County Hospital

🇺🇸

Creve Coeur, Missouri, United States

Parkland Health Center - Farmington

🇺🇸

Farmington, Missouri, United States

Washington University School of Medicine

🇺🇸

Saint Louis, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

Siteman Cancer Center at Christian Hospital

🇺🇸

Saint Louis, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

Glens Falls Hospital

🇺🇸

Glens Falls, New York, United States

Mercy Hospital Washington

🇺🇸

Washington, Missouri, United States

Laura and Isaac Perlmutter Cancer Center at NYU Langone

🇺🇸

New York, New York, United States

East Carolina University

🇺🇸

Greenville, North Carolina, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Columbus Oncology and Hematology Associates

🇺🇸

Dublin, Ohio, United States

Dublin Methodist Hospital

🇺🇸

Dublin, Ohio, United States

Armes Family Cancer Center

🇺🇸

Findlay, Ohio, United States

Blanchard Valley Hospital

🇺🇸

Findlay, Ohio, United States

Orion Cancer Care

🇺🇸

Findlay, Ohio, United States

Central Ohio Breast and Endocrine Surgery

🇺🇸

Gahanna, Ohio, United States

Dayton Physicians LLC-Wayne

🇺🇸

Greenville, Ohio, United States

Mount Carmel Grove City Hospital

🇺🇸

Grove City, Ohio, United States

Greater Dayton Cancer Center

🇺🇸

Kettering, Ohio, United States

Miami Valley Cancer Care and Infusion

🇺🇸

Greenville, Ohio, United States

Wayne Hospital

🇺🇸

Greenville, Ohio, United States

Saint Rita's Medical Center

🇺🇸

Lima, Ohio, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

Kettering Medical Center

🇺🇸

Kettering, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

Mount Carmel New Albany Surgical Hospital

🇺🇸

New Albany, Ohio, United States

Toledo Clinic Cancer Centers-Maumee

🇺🇸

Maumee, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

Springfield Regional Cancer Center

🇺🇸

Springfield, Ohio, United States

Mercy Health - Saint Vincent Hospital

🇺🇸

Toledo, Ohio, United States

University of Cincinnati Cancer Center-West Chester

🇺🇸

West Chester, Ohio, United States

Mercy Health - Saint Anne Hospital

🇺🇸

Toledo, Ohio, United States

Saint Joseph Warren Hospital

🇺🇸

Warren, Ohio, United States

Mercy Health Sylvania Radiation Oncology Center

🇺🇸

Toledo, Ohio, United States

Dayton Physicians LLC - Troy

🇺🇸

Troy, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center

🇺🇸

Wilmington, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

Saint Elizabeth Youngstown Hospital

🇺🇸

Youngstown, Ohio, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Thomas Jefferson University Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Geisinger Cancer Services-Pottsville

🇺🇸

Pottsville, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Asplundh Cancer Pavilion

🇺🇸

Willow Grove, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg

🇺🇸

Lewisburg, Pennsylvania, United States

University of Virginia Cancer Center

🇺🇸

Charlottesville, Virginia, United States

Harrison HealthPartners Hematology and Oncology-Bremerton

🇺🇸

Bremerton, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

Jefferson Healthcare

🇺🇸

Port Townsend, Washington, United States

Kaiser Permanente-San Francisco

🇺🇸

San Francisco, California, United States

Kaiser Permanente San Leandro

🇺🇸

San Leandro, California, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Saint Francis Cancer Center

🇺🇸

Colorado Springs, Colorado, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Boulder Community Foothills Hospital

🇺🇸

Boulder, Colorado, United States

Littleton Adventist Hospital

🇺🇸

Littleton, Colorado, United States

Essentia Health Saint Mary's Medical Center

🇺🇸

Duluth, Minnesota, United States

The Melanoma and Skin Cancer Institute

🇺🇸

Englewood, Colorado, United States

Mercy Medical Center

🇺🇸

Durango, Colorado, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Rocky Mountain Cancer Centers - Centennial

🇺🇸

Centennial, Colorado, United States

Essentia Health Saint Mary's - Detroit Lakes Clinic

🇺🇸

Detroit Lakes, Minnesota, United States

Essentia Health Virginia Clinic

🇺🇸

Virginia, Minnesota, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

Kaiser Permanente-Rock Creek

🇺🇸

Lafayette, Colorado, United States

Rocky Mountain Cancer Centers - Swedish

🇺🇸

Englewood, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

Essentia Health - Jamestown Clinic

🇺🇸

Jamestown, North Dakota, United States

Lake Region Healthcare Corporation-Cancer Care

🇺🇸

Fergus Falls, Minnesota, United States

Essentia Health - Park Rapids

🇺🇸

Park Rapids, Minnesota, United States

Essentia Health Sandstone

🇺🇸

Sandstone, Minnesota, United States

Essentia Health Cancer Center

🇺🇸

Duluth, Minnesota, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

Coborn Cancer Center at Saint Cloud Hospital

🇺🇸

Saint Cloud, Minnesota, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Central Care Cancer Center - Garden City

🇺🇸

Garden City, Kansas, United States

Central Care Cancer Center - Great Bend

🇺🇸

Great Bend, Kansas, United States

Essentia Health Saint Joseph's Medical Center

🇺🇸

Brainerd, Minnesota, United States

Sanford Cancer Center Worthington

🇺🇸

Worthington, Minnesota, United States

Essentia Health - Deer River Clinic

🇺🇸

Deer River, Minnesota, United States

Sanford South University Medical Center

🇺🇸

Fargo, North Dakota, United States

Parker Adventist Hospital

🇺🇸

Parker, Colorado, United States

Essentia Health Hibbing Clinic

🇺🇸

Hibbing, Minnesota, United States

Essentia Health - Moose Lake Clinic

🇺🇸

Moose Lake, Minnesota, United States

Sanford Thief River Falls Medical Center

🇺🇸

Thief River Falls, Minnesota, United States

Southpointe-Sanford Medical Center Fargo

🇺🇸

Fargo, North Dakota, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Essentia Health - Baxter Clinic

🇺🇸

Baxter, Minnesota, United States

Essentia Health - Ely Clinic

🇺🇸

Ely, Minnesota, United States

Riverwood Healthcare Center

🇺🇸

Aitkin, Minnesota, United States

Essentia Health - Fosston

🇺🇸

Fosston, Minnesota, United States

Essentia Health Cancer Center-South University Clinic

🇺🇸

Fargo, North Dakota, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Cancer Center at Saint Joseph's

🇺🇸

Phoenix, Arizona, United States

Banner University Medical Center - Tucson

🇺🇸

Tucson, Arizona, United States

Mercy Hospital Fort Smith

🇺🇸

Fort Smith, Arkansas, United States

CARTI Cancer Center

🇺🇸

Little Rock, Arkansas, United States

Cedars Sinai Medical Center

🇺🇸

Los Angeles, California, United States

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

Holy Cross Hospital

🇺🇸

Fort Lauderdale, Florida, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

🇺🇸

Canton, Michigan, United States

Trinity Health Medical Center - Canton

🇺🇸

Canton, Michigan, United States

Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Fairbanks Memorial Hospital

🇺🇸

Fairbanks, Alaska, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

UM Sylvester Comprehensive Cancer Center at Plantation

🇺🇸

Plantation, Florida, United States

Saint Alphonsus Cancer Care Center-Nampa

🇺🇸

Nampa, Idaho, United States

MedStar Georgetown University Hospital

🇺🇸

Washington, District of Columbia, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

UM Sylvester Comprehensive Cancer Center at Coral Gables

🇺🇸

Coral Gables, Florida, United States

Kootenai Clinic Cancer Services - Sandpoint

🇺🇸

Sandpoint, Idaho, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

MedStar Washington Hospital Center

🇺🇸

Washington, District of Columbia, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center

🇺🇸

Miami, Florida, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

Genesee Cancer and Blood Disease Treatment Center

🇺🇸

Flint, Michigan, United States

Borgess Medical Center

🇺🇸

Kalamazoo, Michigan, United States

UM Sylvester Comprehensive Cancer Center at Aventura

🇺🇸

Aventura, Florida, United States

UM Sylvester Comprehensive Cancer Center at Deerfield Beach

🇺🇸

Deerfield Beach, Florida, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

🇺🇸

Brighton, Michigan, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Corewell Health Lakeland Hospitals - Niles Hospital

🇺🇸

Niles, Michigan, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores

🇺🇸

Norton Shores, Michigan, United States

Boston Medical Center

🇺🇸

Boston, Massachusetts, United States

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

🇺🇸

Baltimore, Maryland, United States

Bronson Methodist Hospital

🇺🇸

Kalamazoo, Michigan, United States

Trinity Health Grand Rapids Hospital

🇺🇸

Grand Rapids, Michigan, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital

🇺🇸

Pontiac, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

🇺🇸

Grosse Pointe Woods, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

🇺🇸

Grand Rapids, Michigan, United States

Memorial Sloan Kettering Basking Ridge

🇺🇸

Basking Ridge, New Jersey, United States

Michigan Healthcare Professionals Pontiac

🇺🇸

Pontiac, Michigan, United States

Ascension Borgess Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Trinity Health Medical Center - Brighton

🇺🇸

Brighton, Michigan, United States

Michigan Breast Specialists-Grosse Pointe Woods

🇺🇸

Grosse Pointe Woods, Michigan, United States

Corewell Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus

🇺🇸

Macomb, Michigan, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

University of Michigan Health - Sparrow Lansing

🇺🇸

Lansing, Michigan, United States

Michigan Breast Specialists-Warren

🇺🇸

Warren, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Toledo Clinic Cancer Centers-Monroe

🇺🇸

Monroe, Michigan, United States

Ascension Saint Joseph Hospital

🇺🇸

Tawas City, Michigan, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

Saint John Macomb-Oakland Hospital

🇺🇸

Warren, Michigan, United States

Benefis Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Academic Hematology Oncology Specialists

🇺🇸

Grosse Pointe Woods, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

🇺🇸

Ypsilanti, Michigan, United States

Trinity Health Muskegon Hospital

🇺🇸

Muskegon, Michigan, United States

Great Lakes Cancer Management Specialists-Rochester Hills

🇺🇸

Rochester Hills, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Professional Building

🇺🇸

Warren, Michigan, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

University of Michigan Health - West

🇺🇸

Wyoming, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

Riverview Medical Center/Booker Cancer Center

🇺🇸

Red Bank, New Jersey, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Kalispell Regional Medical Center

🇺🇸

Kalispell, Montana, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Bozeman Health Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Hackensack University Medical Center

🇺🇸

Hackensack, New Jersey, United States

Jersey Shore Medical Center

🇺🇸

Neptune, New Jersey, United States

Memorial Sloan Kettering Bergen

🇺🇸

Montvale, New Jersey, United States

Saint Alphonsus Cancer Care Center-Ontario

🇺🇸

Ontario, Oregon, United States

Marshfield Medical Center-Marshfield

🇺🇸

Marshfield, Wisconsin, United States

Gibbs Cancer Center-Pelham

🇺🇸

Greer, South Carolina, United States

Huntsman Cancer Institute/University of Utah

🇺🇸

Salt Lake City, Utah, United States

Marshfield Medical Center-Rice Lake

🇺🇸

Rice Lake, Wisconsin, United States

Saint Alphonsus Cancer Care Center-Baker City

🇺🇸

Baker City, Oregon, United States

Northwest Wisconsin Cancer Center

🇺🇸

Ashland, Wisconsin, United States

Gibbs Cancer Center-Gaffney

🇺🇸

Gaffney, South Carolina, United States

ProHealth D N Greenwald Center

🇺🇸

Mukwonago, Wisconsin, United States

North Grove Medical Park

🇺🇸

Spartanburg, South Carolina, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

University of Vermont Medical Center

🇺🇸

Burlington, Vermont, United States

Central Vermont Medical Center/National Life Cancer Treatment

🇺🇸

Berlin, Vermont, United States

Marshfield Clinic-Minocqua Center

🇺🇸

Minocqua, Wisconsin, United States

University of Vermont and State Agricultural College

🇺🇸

Burlington, Vermont, United States

ProHealth Waukesha Memorial Hospital

🇺🇸

Waukesha, Wisconsin, United States

ProHealth Oconomowoc Memorial Hospital

🇺🇸

Oconomowoc, Wisconsin, United States

MGC Hematology Oncology-Union

🇺🇸

Union, South Carolina, United States

Marshfield Clinic-Chippewa Center

🇺🇸

Chippewa Falls, Wisconsin, United States

Essentia Health-Spooner Clinic

🇺🇸

Spooner, Wisconsin, United States

Marshfield Medical Center - Ladysmith

🇺🇸

Ladysmith, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center

🇺🇸

Wisconsin Rapids, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point

🇺🇸

Stevens Point, Wisconsin, United States

Essentia Health Saint Mary's Hospital - Superior

🇺🇸

Superior, Wisconsin, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

The Women's Imaging Center

🇺🇸

Denver, Colorado, United States

Porter Adventist Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

Western Surgical Care

🇺🇸

Denver, Colorado, United States

Ascension Saint John Hospital

🇺🇸

Detroit, Michigan, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

University of Arizona Cancer Center-North Campus

🇺🇸

Tucson, Arizona, United States

Mission Hope Medical Oncology - Arroyo Grande

🇺🇸

Arroyo Grande, California, United States

Kaiser Permanente- Marshall Medical Offices

🇺🇸

Redwood City, California, United States

Mercy Cancer Center - Rocklin

🇺🇸

Rocklin, California, United States

Kaiser Permanente-Roseville

🇺🇸

Roseville, California, United States

Kaiser Permanente-Santa Teresa-San Jose

🇺🇸

San Jose, California, United States

Pacific Central Coast Health Center-San Luis Obispo

🇺🇸

San Luis Obispo, California, United States

Kaiser San Rafael-Gallinas

🇺🇸

San Rafael, California, United States

Kaiser Permanente-Santa Rosa

🇺🇸

Santa Rosa, California, United States

Kaiser Permanente Medical Center - Santa Clara

🇺🇸

Santa Clara, California, United States

Mission Hope Medical Oncology - Santa Maria

🇺🇸

Santa Maria, California, United States

Kaiser Permanente-South San Francisco

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Stockton

🇺🇸

Stockton, California, United States

Kaiser Permanente Medical Center-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Vallejo

🇺🇸

Vallejo, California, United States

Kaiser Permanente-Walnut Creek

🇺🇸

Walnut Creek, California, United States

BASS Medical Group - Lennon

🇺🇸

Walnut Creek, California, United States

Kaiser Permanente-Lone Tree

🇺🇸

Lone Tree, Colorado, United States

Emory University Hospital/Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

Northside Hospital - Duluth

🇺🇸

Duluth, Georgia, United States

Northside Hospital

🇺🇸

Atlanta, Georgia, United States

Northside Hospital - Gwinnett

🇺🇸

Lawrenceville, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Anthony's Health

🇺🇸

Alton, Illinois, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

SIH Cancer Institute

🇺🇸

Carterville, Illinois, United States

Saint Mary's Hospital

🇺🇸

Centralia, Illinois, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Dixon

🇺🇸

Dixon, Illinois, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Elmhurst Memorial Hospital

🇺🇸

Elmhurst, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

Northwestern Medicine Lake Forest Hospital

🇺🇸

Lake Forest, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Good Samaritan Regional Health Center

🇺🇸

Mount Vernon, Illinois, United States

Edward Hospital/Cancer Center

🇺🇸

Naperville, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Memorial Medical Center

🇺🇸

Springfield, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Mary Greeley Medical Center

🇺🇸

Ames, Iowa, United States

Reid Health

🇺🇸

Richmond, Indiana, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Methodist West Hospital

🇺🇸

West Des Moines, Iowa, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Saint Joseph London

🇺🇸

London, Kentucky, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

Mercy Health - Paducah Medical Oncology and Hematology

🇺🇸

Paducah, Kentucky, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

🇺🇸

Grand Rapids, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

Saint Louis Cancer and Breast Institute-Ballwin

🇺🇸

Ballwin, Missouri, United States

Central Care Cancer Center - Bolivar

🇺🇸

Bolivar, Missouri, United States

Cox Cancer Center Branson

🇺🇸

Branson, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

MU Health Care Goldschmidt Cancer Center

🇺🇸

Jefferson City, Missouri, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

Lake Regional Hospital

🇺🇸

Osage Beach, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

Delbert Day Cancer Institute at PCRMC

🇺🇸

Rolla, Missouri, United States

Mercy Hospital South

🇺🇸

Saint Louis, Missouri, United States

Siteman Cancer Center-South County

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Siteman Cancer Center at Saint Peters Hospital

🇺🇸

Saint Peters, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

BJC Outpatient Center at Sunset Hills

🇺🇸

Sunset Hills, Missouri, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Community Medical Center

🇺🇸

Scranton, Pennsylvania, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

Memorial Sloan Kettering Monmouth

🇺🇸

Middletown, New Jersey, United States

Memorial Sloan Kettering Westchester

🇺🇸

Harrison, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Memorial Sloan Kettering Commack

🇺🇸

Commack, New York, United States

Memorial Sloan Kettering Nassau

🇺🇸

Uniondale, New York, United States

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

Duke Cancer Institute Cary

🇺🇸

Cary, North Carolina, United States

Sanford Medical Center Fargo

🇺🇸

Fargo, North Dakota, United States

Duke Women's Cancer Care Raleigh

🇺🇸

Raleigh, North Carolina, United States

Duke Raleigh Hospital

🇺🇸

Raleigh, North Carolina, United States

Indu and Raj Soin Medical Center

🇺🇸

Beavercreek, Ohio, United States

UH Seidman Cancer Center at UH Avon Health Center

🇺🇸

Avon, Ohio, United States

UHHS-Chagrin Highlands Medical Center

🇺🇸

Beachwood, Ohio, United States

Saint Elizabeth Boardman Hospital

🇺🇸

Boardman, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Dayton Physicians LLC-Miami Valley South

🇺🇸

Centerville, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

Miami Valley Hospital South

🇺🇸

Centerville, Ohio, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood

🇺🇸

Cincinnati, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital

🇺🇸

Franklin, Ohio, United States

Dayton Physicians LLC-Atrium

🇺🇸

Franklin, Ohio, United States

Zangmeister Center Grove City

🇺🇸

Grove City, Ohio, United States

Memorial Hospital

🇺🇸

Marysville, Ohio, United States

Mercy Health Perrysburg Cancer Center

🇺🇸

Perrysburg, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center

🇺🇸

Sandusky, Ohio, United States

Springfield Regional Medical Center

🇺🇸

Springfield, Ohio, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Pocono Medical Center

🇺🇸

East Stroudsburg, Pennsylvania, United States

Lehigh Valley Hospital-Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Penn State Milton S Hershey Medical Center

🇺🇸

Hershey, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

Saint Michael Cancer Center

🇺🇸

Silverdale, Washington, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

Duluth Clinic Ashland

🇺🇸

Ashland, Wisconsin, United States

Essentia Health-Hayward Clinic

🇺🇸

Hayward, Wisconsin, United States

Miller-Dwan Hospital

🇺🇸

Duluth, Minnesota, United States

Upper Valley Medical Center

🇺🇸

Troy, Ohio, United States

Marshfield Clinic-Wausau Center

🇺🇸

Wausau, Wisconsin, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

Marshfield Medical Center - Weston

🇺🇸

Weston, Wisconsin, United States

Kaiser Permanente Downtown Commons

🇺🇸

Sacramento, California, United States

Mercy Cancer Center - Sacramento

🇺🇸

Sacramento, California, United States

Kaiser Permanente-South Sacramento

🇺🇸

Sacramento, California, United States

South Sacramento Cancer Center

🇺🇸

Sacramento, California, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

Kaiser Permanente Moanalua Medical Center

🇺🇸

Honolulu, Hawaii, United States

Mission Cancer and Blood - Des Moines

🇺🇸

Des Moines, Iowa, United States

Broadlawns Medical Center

🇺🇸

Des Moines, Iowa, United States

Iowa Methodist Medical Center

🇺🇸

Des Moines, Iowa, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

🇺🇸

Ann Arbor, Michigan, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel

🇺🇸

Des Moines, Iowa, United States

Iowa Lutheran Hospital

🇺🇸

Des Moines, Iowa, United States

Saint Joseph Hospital

🇺🇸

Lexington, Kentucky, United States

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

UNC Lineberger Comprehensive Cancer Center

🇺🇸

Chapel Hill, North Carolina, United States

Miami Valley Hospital

🇺🇸

Dayton, Ohio, United States

Premier Blood and Cancer Center

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Dayton Physician LLC - Englewood

🇺🇸

Dayton, Ohio, United States

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

🇺🇸

Saint Joseph, Michigan, United States

Ascension Saint Mary's Hospital

🇺🇸

Saginaw, Michigan, United States

Corewell Health Lakeland Hospitals - Saint Joseph Hospital

🇺🇸

Saint Joseph, Michigan, United States

Marshfield Medical Center-EC Cancer Center

🇺🇸

Eau Claire, Wisconsin, United States

Saint Anthony Regional Hospital

🇺🇸

Carroll, Iowa, United States

Essentia Health - International Falls Clinic

🇺🇸

International Falls, Minnesota, United States

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