The Diastolic Pressure Gradient for Patients With Acute Coronary Syndrome: Evaluation of Non Culprit Lesions

• Conditions: Functional Evaluation of Non Culprit Lesions in ACS Patients
• Interventions: Other: Measurement of intracoronary pressure

• Registration Number: NCT01671631
• Lead Sponsor: University Magna Graecia

Brief Summary

The assessment of non-culprit stenoses is an important issue in ACS. Adenosine administration is currently required for functional evaluation of stenosis severity using the fractional flow reserve (FFR). An alternative adenosine-independent index of coronary stenosis, the instantaneous wave-free ratio (iFR), was recently introduced.

Aim of the present study will be to evaluate the trans-stenotic instantaneous wave-free pressure gradient (iFG), the instantaneous wave-free ratio (iFR) and the fractional flow reserve (FFR) in ACS patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-08
• Study First Submitted: 2012-08-20
• Study First Submitted QC: 2012-08-22
• Last Update Submitted: 2012-08-22
• Study First Posted: 2012-08-23
• Last Update Posted: 2012-08-23

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• age 40 to 80 years
• recent Acute Coronary Syndrome
• indication for coronary angiography
• presence of at least one non-culprit lesion requiring functional evaluation with fractional flow reserve (FFR):

Exclusion Criteria

• Haemodynamically significant valvular disease
• controindication for Adenosin administration
• previous CABG on the index vessel

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Acute Coronary Syndrome	Measurement of intracoronary pressure	Patients with Acute Coronary Syndrome and multivessel coronary artery disease undergoing functional evaluation of non-culprit lesions.

Trial Locations

Locations (1)

Cardiologia Interventistica UMG; 🇮🇹 Catanzaro, Calabria, Italy