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Clinical Evaluation of ZiyinChushi Decoction in the Treatment of Atopic Dermatitis with Yin Deficiency and Dampness Accumulation Syndrome

Phase 1
Conditions
Atopic Dermatitis
Registration Number
ITMCTR2022000042
Lead Sponsor
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1 Meet the Chinese AD diagnostic criteria proposed by ZHANG Jian-zhong in the Chinese Guidelines for the Diagnosis and Treatment of Atopic Dermatitis;
2 Age 18 to 70 (including 18 and 70);
3 SCORAD score of 25 to 50 (including 25 and 50);
4 Meet the diagnostic criteria of Yin Deficiency and Damp Love Syndrome in traditional Chinese medicine;
5 Sign the informed consent.

Exclusion Criteria

1 Patients with any other systemic or active skin diseases (such as acute allergic dermatitis, psoriasis, lupus erythematosus) that may affect the evaluation of the test results; or have scars, tattoos, birthmarks or other pigments at the skin lesions Patients with sexual dermatosis, etc., which can affect the evaluation of skin lesions;
2. Patients with serious primary diseases such as heart, cerebrovascular, liver, kidney, gastrointestinal tract, hematopoietic system, endocrine, etc., as well as patients with mental diseases;
3. Pregnant, lactating women and those who are about to become pregnant in the past 3 months;
4. Patients who have used biological agents within 28 days before treatment; patients who have systematically used antihistamines, glucocorticoids, immunosuppressants and other therapeutic drugs within 14 days before treatment; or topical glucocorticoids and calcineurin within 7 days before treatment Patients with therapeutic drugs such as inhibitors;
5 Those who are participating in other clinical trials during the trial observation period;
6 Those who are allergic to the drug in this study.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Scoring Atopic Dermatitis Index (SCORAD);
Secondary Outcome Measures
NameTimeMethod
TCM symptom/sign record;Dermatology Life Quality Index (DLQI);
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