The effect of augmentation of Gabapentin and Memantine with Selective Serotonin Re uptake Inhibitors (SSRIs) in treatment of patients with Obsessive Compulsive Disorder (OCD).
Not Applicable
- Conditions
- Obsessive Compulsive Disorder.Obsessive Compulsive Disorder
- Registration Number
- IRCT2016062623705N6
- Lead Sponsor
- Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences , Kermanshah Univers
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Diagnosis of obsessive-compulsive disorder according to the DSM-5 by psychologist; patients that their first reference for treatment or at least one month from cutting drug treatment is passed; Age range 20-40 years.
Exclusion criteria: History of organic disease Seizures, diabetes, liver or kidney failure, hypothyroidism; Concomitant use of cardiac medications, Blood pressure, hormones, thyroid; Having other major psychiatric disease and substance abuse; Medical allergy to SSRI, Memantine with Gabapentin; Unwillingness participate in the study; Require hospitalization or receive ECT.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Obsessive-compulsive disorder. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Based on the severity of obsessive-compulsive disorder.
- Secondary Outcome Measures
Name Time Method