跳至主要内容
临床试验/NCT06500312
NCT06500312招募中不适用

Assessment the Association of Imaging and Tumor Microenvironment in Lung Cancer With Radiogenomics

Wuhan Union Hospital, China1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2024年7月2日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
150
试验地点
1
主要终点
Correlation analysis of sequencing results and body composition

研究概览

简要总结

This is the prospective, observational cohort study (Radiogenomics-Lung), which aims to explore the relationship between the imaging information of lung cancer patients, tumor microenvironment and the prognosis of lung cancer patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients were treated for lung cancer in Wuhan Union Hospital from July 2024 to July 2027;
  • Aged > 18 years old;
  • At least one chest CT scan before treatment;
  • Tissue biopsy pathological examination confirmed the diagnosis of the above tumors.

排除标准

  • Poor image quality;
  • Incomplete clinical data or loss of follow-up;
  • Presence of another primary malignancy other than lung cancer;
  • Unclear pathological diagnosis。

结局指标

主要结局

Correlation analysis of sequencing results and body composition

时间窗: 0.5 year

Conducting correlation analysis between body composition and results of multi-omics sequencing

Correlation analysis of sequencing results and tumor radiomic features

时间窗: 0.5 year

Conducting correlation analysis between radiomic features and results of multi-omics sequencing

次要结局

  • Constructing tumor microenvironment prediction model(2 years)
  • Constructing a multi-dimensional prognostic prediction model(3 years)

研究者

发起方
Wuhan Union Hospital, China
申办方类型
Other
责任方
Sponsor

研究点 (1)

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