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Clinical Trials/NCT06500312
NCT06500312
Recruiting
Not Applicable

Assessment the Association of Imaging and Tumor Microenvironment in Lung Cancer With Radiogenomics

Wuhan Union Hospital, China1 site in 1 country150 target enrollmentJuly 2, 2024
ConditionsLung Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung Cancer
Sponsor
Wuhan Union Hospital, China
Enrollment
150
Locations
1
Primary Endpoint
Correlation analysis of sequencing results and body composition
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This is the prospective, observational cohort study (Radiogenomics-Lung), which aims to explore the relationship between the imaging information of lung cancer patients, tumor microenvironment and the prognosis of lung cancer patients.

Registry
clinicaltrials.gov
Start Date
July 2, 2024
End Date
July 2, 2027
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Wuhan Union Hospital, China
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients were treated for lung cancer in Wuhan Union Hospital from July 2024 to July 2027;
  • Aged \> 18 years old;
  • At least one chest CT scan before treatment;
  • Tissue biopsy pathological examination confirmed the diagnosis of the above tumors.

Exclusion Criteria

  • Poor image quality;
  • Incomplete clinical data or loss of follow-up;
  • Presence of another primary malignancy other than lung cancer;
  • Unclear pathological diagnosis。

Outcomes

Primary Outcomes

Correlation analysis of sequencing results and body composition

Time Frame: 0.5 year

Conducting correlation analysis between body composition and results of multi-omics sequencing

Correlation analysis of sequencing results and tumor radiomic features

Time Frame: 0.5 year

Conducting correlation analysis between radiomic features and results of multi-omics sequencing

Secondary Outcomes

  • Constructing tumor microenvironment prediction model(2 years)
  • Constructing a multi-dimensional prognostic prediction model(3 years)

Study Sites (1)

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