NCT06537037
Recruiting
Not Applicable
Exploring the Association of Imaging and Tumor Microenvironment in Urologic Cancer Using Radiogenomic Approach（Radiogenomics-Urinary）
Wuhan Union Hospital, China1 site in 1 country150 target enrollmentAugust 2024
ConditionsUrologic Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Urologic Cancer
- Sponsor
- Wuhan Union Hospital, China
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Correlation analysis of sequencing results and tumor radiomic features
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This is the prospective, observational cohort study (Radiogenomics-Urinary), which aims to explore the relationship between the imaging information of urologic cancer patients, tumor microenvironment and the prognosis of urologic cancer patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients treated for urologic cancer in Wuhan Union Hospital from August 2024 to August 2027;
- •Aged \> 18 years old;
- •At least one CT scan or MRI scan before treatment;
- •Tissue biopsy pathological examination confirmed the diagnosis of the above tumors.
- •Exclusion criteria：
- •Poor image quality;
- •Incomplete clinical data or loss of follow-up;
- •Presence of another primary malignancy other than urologic cancer;
- •Unclear pathological diagnosis。
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Correlation analysis of sequencing results and tumor radiomic features
Time Frame: 0.5 year
Conducting correlation analysis between radiomic features and results of multi-omics sequencing.
Correlation analysis of sequencing results and body composition
Time Frame: 0.5 year
Conducting correlation analysis between body composition and results of multi-omics sequencing.
Secondary Outcomes
- Constructing a multi-dimensional prognostic prediction model(3 years)
- Constructing tumor microenvironment prediction model(2 years)
Study Sites (1)
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