Comparative Evaluation of Silver Nano Particles with PRF Vs PRF With Xenograft In Two-Walled Intra-bony Defects: A Clinico-Radiographic study
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Radiographic Depth of Intra bony Defect
研究概览
简要总结
Platelet rich fibrin with bone graft is routinely used as regenerative material in Periodontology for augmentation of lost bone. Silver nanoparticles are used for medical purposes in wound dressisngs, ointments and orthopedic implants and silver impregnated sutures. Silver nanoparticles have wound healing properties as well as potential osteogenic properties aiding regeneration of of bone.
The patients meeting the inclusion criteria will be evaluated and alloted in
Group A : PRF with AgNPs
Group B : PRF with xenograft
Open Flap debridement of both groups will be done and placement of designated material will be placed in the defect followed by closure with sutures.
Pre and Post operative evaluation of Probing depth, Clinical Attachment level and radiographic bone depth is compared along with healing of soft tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Periodontitis Within 25 to 55 Years of Age Probing Pocket Depth more than 5 Mm Evidence Of two-walled Angular defects as determined by intraoral periapical radiograph.
排除标准
- •Undergoing Anti – coagulant therapy Systemic Conditions such as Myocardial Infarction, Stroke, Renal diseases, Carcinoma etc In the Past 6 Months Adverse Habit such as Tobacco consumption & Smokers Pregnant & Lactating Women.
结局指标
主要结局
Radiographic Depth of Intra bony Defect
时间窗: at 6 months
次要结局
- Increase in Clinical Attachment Level Probing depth(2 weeks, 4 weeks, 3 month, 6 month)