The efficacy of ultrasound-guided interpectoral plane block combined with multiple-injection costotransverse block or single-injection erector spinae plane block compared to systemic analgesia for postoperative pain control in breast cancer surgery: A randomized controlled trial
Phase 3
Recruiting
- Conditions
- postoperative pain control in breast cancer surgeryBreast cancer , breast cancer surgery,costotransverse block ,pain controlled,costotransverse block,erector spinae plane block
- Registration Number
- TCTR20230103005
- Lead Sponsor
- Department of Anesthesiology, Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University, Chiang Mai, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
1. Female patients aged between 20 and 65 years
2. American Society of Anesthesia (ASA) physical status I - II
3. Scheduled for elective unilateral breast cancer surgery
4. Body weight > 40 kg
Exclusion Criteria
1. Patients with known allergies to any of the study drugs (local anesthetics, opioids, acetaminophen, and codigesic)
2. Underlying chronic kidney disease, liver cirrhosis, major cardiac disease, or pre-existing neurological deficits
3. Recent use of opioid drugs.
4. Morbid obesity (body mass index > 40 kg/m2)
5. Coagulopathy
6. Pre-existing infection at the block site
7. Psychological diseases include bipolar or depression
8. Inability to communicate include deafness or no telephone available
9. Bilateral breast surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method postoperative morphine consumption in the first 24 hours 24 hr post-operative measure by mg,intraoperative fentanyl consumption, postoperative pain scores, block performance data, nausea and vomiting, patient satisfaction. post-op 48hr , 2 wk mg/NRS/pain severity index,patient satisfaction, and the incidence of post mastectomy pain. 2 wk NRS,PSI
- Secondary Outcome Measures
Name Time Method Total morphine consumption in the first 24 postoperative hours record