Respiatory Viral Infections in Patients with Multiple Myeloma

Completed

• Conditions: Multiple Mieloma; Respiratory Viral Infections

• Registration Number: NCT06810115
• Lead Sponsor: University Medical Centre Ljubljana

Brief Summary

Respiratory viruses are known to be a major cause of morbodity in multiple myeloma patients but prospective long-term sudies are lacking. We analysed 219 multiple myeloma patients that had 554 nasopharingeal swabs with 58 documented viral episodes. Respiratory viruses studied were rhinovirus, enterovirus, parainflienza, respirator, syncytial virus, metapneumovirus, coronavirus, bocavirus, influenza A, influenza B. Clinical data were extracted from a prospectively entered database, medical records were reviewed. We have prospectively studiend patients until May 2019 when we gathered survival data. Lastly because of Covid-19 pandemic when almost no other viral infections were isolated, we analysed clinical course of respiratory infections in patients with multiple myeloma after the pandemic.

Detailed Description

Not available

Study Timeline

• Status Verified: 2015-03
• Study Start: 2015-10-01
• Primary Completion: 2019-05-01
• Study Completion: 2024-10-01
• Study First Submitted: 2025-01-30
• Study First Submitted QC: 2025-01-30
• Last Update Submitted: 2025-01-30
• Study First Posted: 2025-02-05
• Last Update Posted: 2025-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 219

Inclusion Criteria

• Patients with multiple myeloma

Exclusion Criteria

Other hematological malignancies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of respiratory viral infections in patirnts with multiple myeloma	1 year