Effect of Short-term Oxygen During CPET in Pulmonary Hypertension

Phase 2

Completed

• Conditions: Chronic Cardiorespiratory Disease; Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension

• Registration Number: NCT01748474
• Lead Sponsor: University of Zurich

Brief Summary

In a randomized, sham-controlled trial the investigators will test whether supplemental oxygen given during cardiopulmonary exercise testing will improve exercise performance and physiological parameters in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-10-04
• Study Start: 2012-12
• Study First Submitted QC: 2012-12-11
• Study First Posted: 2012-12-12
• Primary Completion: 2016-03
• Study Completion: 2016-07
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-11
• Last Update Posted: 2016-08-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Watt	1 day
exercise time	1 day

Secondary Outcome Measures

Name	Time	Method
Changes in arterial blood parameters	1 day
Peak oxygen uptake	1 day
Respiratory exchange ratio	1 day
ventilatory equivalent of carbon dioxide (VE/VCO2) slope	1 day
end-tidal pressures of carbon dioxide (PET CO2)	1 day

Trial Locations

Locations (1)

University Hospital Zurich, Division of Pneumology; 🇨🇭 Zurich, ZH, Switzerland