asal High Flow therapy for Infants and Children with Acute Hypoxemic Respiratory Failure - Pilot Trial

Phase 3

Active, not recruiting

• Conditions: Acute Respiratory Failure; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12615001305516
• Lead Sponsor: ady Cilento Children's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-30
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 576

Inclusion Criteria

Children aged 0-16 years of age with the clinical diagnosis of an Acute Hypoxemic Respiratory Failure disease process such as acute lower respiratory tract infection or asthma, or pnuemonia as examples, and an oxygen requirement in room air (SpO2 <92%)
Included are infants with reactive airway disease >12 months and an oxygen requirement in room air (SpO2 <92%). This includes infants >12 months with the diagnosis of bronchiolitis.
Informed consent from parents or guardians

Exclusion Criteria

Upper airway obstruction
Craniofacial malformations
Critically ill infants requiring immediate higher level of respiratory support i.e. NIV or invasive ventilation, low level of consciousness.
Basal skull fracture
Cyanotic Heart Disease
Home Oxygen therapy
Apnoeas (defined as requiring respiratory support such as NIV or mechanical ventilation)
Upper airway obstruction
Trauma
Cystic Fibrosis
Oncology patients
Palliative Care patients
Previous use of NHF therapy
Child protection case

Study & Design

• Study Type: Interventional
• Study Design: Not specified