Prospective study to the Optimal duration of Compression Therapy As prevention of chronic Venous Insufficiency After deep venous thrombosis
Completed
- Conditions
- post-thrombotic syndromechronic complaints of the leg after deep vein thrombosis1004704310014523
- Registration Number
- NL-OMON35400
- Lead Sponsor
- Diakonessenhuis Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 516
Inclusion Criteria
all patients with one year adequate therapy after echo duplex proven proximal DVT of the leg
informed consent
Exclusion Criteria
recurrent ipsilateral DVT (known riskfactor of PTS)
PTS developped in first year post-thrombosis
DVT only distal of popliteal vein
contra-indication for (stopping) compression therapy as indicated by treating physician
no informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary outcome:<br /><br>- The incidence of PTS in the second post-thrombotic year after one versus two<br /><br>years of ambulant compression therapy</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secundary outcomes:<br /><br>- Can venous ultrasound discriminate between patients after one year ACT in<br /><br>risk of developing PTS<br /><br>- Can baseline characteristics be used as prognostic markers for developing PTS<br /><br>- What influence does (the absense of) ACT and PTS has on quality of life</p><br>