跳至主要内容
临床试验/NCT02163148
NCT02163148已完成不适用

Predictors of Exposure Success in Public Speaking Anxiety

University of California, San Diego1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2014年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
Change in peak Subjective Unit of Distress (SUDS) rating from first to fourth (last) exposure

研究概览

简要总结

Anxiety disorders are common and impairing. Although exposure therapy is one of the most effective treatments for anxiety, some individuals do not fully respond to treatment, and these individual differences are not well understood. Exposure therapy involves repeated, deliberate, safe engagement with a feared stimulus without the feared outcome occurring. This treatment is thought to work through a type of emotional learning called fear extinction. This study aims to look at links between fear extinction learning and exposure success, with the overall goal of better understanding who is likely to respond best to exposure therapy and why.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Score of at least 20 on the PRCS
  • Age 18-55
  • English fluency

排除标准

  • Psychotropic medication use in the past 4 weeks
  • Past experience with exposure based therapy
  • History of bipolar disorder, psychotic disorder, or substance dependence
  • Current major depressive disorder of greater than moderate severity (defined as a score on the 9 item Patient Health Questionnaire of greater than 14)
  • Clinically significant suicidal or homicidal ideation
  • Non-removable ferrous metal
  • Current significant neurological conditions
  • History of loss of consciousness greater than 5 minutes duration
  • Claustrophobic

结局指标

主要结局

Change in peak Subjective Unit of Distress (SUDS) rating from first to fourth (last) exposure

时间窗: 90 minutes

Participants will complete 4 exposures during one 90 minute session. Change in the peak ratings on the final exposure relative to the first exposure will be the outcome measure.

次要结局

  • Change from baseline on the Liebowitz Social Anxiety Scale (LSAS) at 2 weeks(Baseline, week 2)
  • Change from baseline on the Personal Report of Confidence as a Speaker (PRCS) at 2 weeks(Baseline, week 2)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tali Manber Ball

Doctoral Candidate

University of California, San Diego

研究点 (1)

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