NL-OMON54371尚未招募不适用
ncovering Pathophysiologic Mechanisms of Treatment Resistant Depression: A comparison with non-TRD patients - UNCOVER-TRD
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 83
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Males and females between 18-70 years of age
- •- First or recurrent episode of unipolar major depressive disorder
- •- Treatment resistance for at least two antidepressants for the TRD group
- •- Never or only once being treated with antidepressants without effect for the
- •non-TRD group
排除标准
- •- ECT within one year prior to the current course
- •- Current use of antidepressants, antipsychotics and mood stabilizers
- •- Use of benzodiazepines within 24 hours before ECT
- •- Use of anti-inflammatory drugs for more than a week in the past month (for
- •patients included for PET-scan only)
- •- Use of immune suppressants (for patients included for PET-scan only)
- •- Presence of current or past relevant somatic disorder
- •- Presence of comorbid bipolar disorder, schizophrenia or substance abuse
- •- MRI- or PET-related exclusion criteria
- •- ECT-related exclusion criteria(for TRD group only)
- •- Low-affinity binder for TSPO (for patients included for PET-scan only)
研究者
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