MedPath

ECGi of SyncAV With MultiPoint Pacing

Completed
Conditions
Cardiac Resynchronization Therapy
Registration Number
NCT06444386
Lead Sponsor
Abbott Medical Devices
Brief Summary

The objective of this clinical study was to evaluate the impact of Multipoint Pacing (MPP) and SyncAV programming on ventricular electrical activation time and activation sequence using noninvasive electrocardiographic imaging (ECGi) in patients receiving cardiac resynchronization therapy (CRT).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Patients previously implanted with a SyncAV and MPP-enabled Abbott Quadripolar CRT pacing system
  • Patient must be > 18 years of age, able to provide informed consent and willing to comply with study requirements
  • Sinus (or atrial paced) rhythm with intact AV conduction with PR interval ≤ 250 ms
  • Patient has documented Left Bundle Branch Block (LBBB)
Exclusion Criteria
  • Resting heart rate > 100 bpm
  • AV Block (1st degree with PR> 250 ms, 2nd or 3rd degree)
  • Documented persistent atrial tachycardia or atrial fibrillation at the moment of enrollment or patients not likely to remain in sinus (or atrial paced) rhythm for the duration of the study
  • Recent (< 3 months) myocardial infarction, ablation, electrolyte imbalance, or any condition within the last 90 days that would contraindicate for CRT programming changes in the opinion of the investigator
  • Women who are pregnant or plan to become pregnant during the study course

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Left ventricular activation time1 day

Evaluate acute changes in left ventricular (LV) electrical activation time measured with ECGi resulting from various CRT pacing configurations with MPP and SyncAV

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Abbott

🇺🇸

Sylmar, California, United States

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